Results 211 to 220 of about 236,702 (302)

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Wedge resection for pulmonary sequestration guided by indocyanine green fluorescence and 3-dimensional reconstruction. [PDF]

JTCVS Tech
Liang Q, Lin S, Chen Z, Guo Z, Gao Q, Yang X, Tian H, Wu Y, Zhong W, Nie Q.   +9 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

DRIFteRS: A dataset of drift invertebrate densities in streams and rivers across western North America, 1997-2024. [PDF]

Ecology
Toskey EK, Matsuoka T, Kiffney PM, Naman SM, Liermann MC, Bailey J, Beauchamp DA, Bellmore JR, Binckley CA, Blumenshine S, Caldwell TJ, Carey MP, Claeson S, Clawson C, Cox R, Cromwell KJ, Danehy RJ, Dodrill MJ, Duda JJ, Fellman JB, Grimm AZ, Hallbert TB, Jordan CE, Keeley ER, Kennedy BP, Kennedy TA, Kohler AE, Lowery ED, Macneale K, Martens KD, Morley SA, Muehlbauer JD, Neuswanger JB, O'Dowd A, Pneh S, Power M, Rhoades SJ, Rosenfeld J, Rossi G, Sanderson BL, Shelby KK, Starkey-Owens T, Thompson JN, Volk C, Williamshen JS, Wisseman RW.   +45 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Considerations for managing legacy phosphorus in the Western Lake Erie Basin. [PDF]

J Environ Qual
Johnson LT, Baird T, Selzer M.
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Hydrochemical characterization and irrigation suitability mapping of groundwater in Pashupathihal subwatershed, karnataka. [PDF]

Sci Rep
Hussain KNJ, Jagadeesh BR, Manjunatha MV, Gundlur SS, Rajkumar GR, Priya P.   +5 more
europepmc   +1 more source