Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Apple leaf disease severity grading based on deep learning and the DRL-Watershed algorithm. [PDF]
Bi Z +7 more
europepmc +1 more source
Trees, Earth, Water, and Ecological Upheaval: Logging Practices and Watershed Protection in California [PDF]
David M. Wilson
openalex +1 more source
Identifying prognostic targets in metastatic prostate cancer beyond AR
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng +13 more
wiley +1 more source
Riparian vegetation layers differ three years after mixed severity wildfire in Oregon. [PDF]
Six LJ, Verschuyl J, Coble AA.
europepmc +1 more source
Determination of Peak Discharge and Design Hydrographs for Small Watersheds in Indiana
I-Pai Wu, J. Delleur, M. H. Diskin
openalex +2 more sources
Runoff from a paved small watershed at White Sands Missile Range, New Mexico [PDF]
Wilbur C. Ballance, J.A. Basler
openalex +1 more source
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian +6 more
wiley +1 more source
An application of farm planning to watershed development
John Murray Nickel Cormack
openalex +2 more sources
Maximizing the potential benefits of beaver restoration for fire resilience and water storage. [PDF]
Moravek JA +10 more
europepmc +1 more source

