Results 31 to 40 of about 10,543,229 (234)

Design Formulae of Wave Transmission due to Oblique Waves at Low Crested Structures

open access: yesJurnal Teknik Sipil, 2011
Low crested structures, including submerged breakwaters, may be provided to protect the beach from wave attack. These structures can be built parallel to the shoreline and the crest is set up at or below water levels. It function is to protect the beach
I Gusti Bagus Siladharma
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

A Subgrid‐Scale Parameterization of Wave‐Structure Interactions for Spectral Wave Models: Idealized Simulations in Offshore Wind Farm Conditions

open access: yesJournal of Advances in Modeling Earth Systems
Extensive offshore renewable energy installations have raised concerns about their environmental impacts. These concerns highlight the need for high fidelity modeling of conditions within wind‐farm regions, where wave–structure interactions through ...
Biao Zhao   +3 more
doaj   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

open access: yesFEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi   +8 more
wiley   +1 more source

Comparative Analysis of High-Fidelity and Reduced-Order Models for Nonlinear Wave–Bathymetry and Wave–Structure Interactions

open access: yesJournal of Marine Science and Engineering
This paper presents a computational study of wave–bathymetry and wave–structure interaction problems using advanced numerical techniques based on high-fidelity, two-phase Navier–Stokes (TpNS) flow and reduced-order, fully nonlinear potential flow models.
Wen-Huai Tsao, Christopher E. Kees
doaj   +1 more source

Smoothed Particle Hydrodynamics Simulation of Wave Overtopping Characteristics for Different Coastal Structures

open access: yesThe Scientific World Journal, 2012
This research paper presents an incompressible smoothed particle hydrodynamics (ISPH) technique to investigate a regular wave overtopping on the coastal structure of different types.
Jaan Hui Pu, Songdong Shao
doaj   +1 more source

HAMS: A Frequency-Domain Preprocessor for Wave-Structure Interactions—Theory, Development, and Application

open access: yesJournal of Marine Science and Engineering, 2019
This paper presents the theoretical background, the numerical implementation, and the applications of a new software that has been developed in recent years for the analysis of wave-structure interactions.
Yingyi Liu
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian   +8 more
wiley   +1 more source

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