Results 191 to 200 of about 38,857 (309)

Atrial fibrosis in atrial fibrillation: Mechanisms, mapping techniques and clinical applications

The Journal of Physiology, EarlyView.
Abstract figure legend Summary of key aspects of atrial fibrosis in atrial fibrillation, highlighting atrial fibrosis as a hallmark of atrial fibrillation (AF). (1) Different types of fibrosis (blue), illustrating reparative and reactive fibrosis; (2) fibrosis detection techniques (green), illustrating late gadolinium enhancement cardiac magnetic ...
Caterina Vidal Horrach, Laura Bevis, Cynthia Nwanna, Alexander M Zolotarev, Mahmoud Ehnesh, Semhar Biniam Misghina, Sayed Al‐Aidarous, Shohreh Honarbakhsh, Caroline H. Roney   +8 more
wiley   +1 more source

In silico predictions of action potential propagation in doxorubicin cardiotoxicity: A parametric study using preclinical 3D magnetic resonance imaging‐based fibrotic left ventricle models

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the study's methodology and key findings. In a preclinical swine model, doxorubicin administration induced cardiotoxicity, characterized by diffuse fibrotic remodelling and altered electrical function, as assessed by magnetic resonance (MR) imaging and electrophysiological mapping.
Javier Villar‐Valero, Jairo Rodríguez Padilla, Nicolas Cedilnik, Buntheng Ly, Juan F. Gomez, Maxime Sermesant, Mihaela Pop, Beatriz Trenor   +7 more
wiley   +1 more source

Electrodiffusion in cardiac intercalated disc nanostructures alters cell–cell action potential transmission via ephaptic coupling: A model study

The Journal of Physiology, EarlyView.
Abstract figure legend Ephaptic phenomena in a high‐resolution model of the cardiac intercalated disc. Meshed representation of a tortuous intercalated disc that was generated based on electron and super‐resolution microscopy data. Na+ channels (red) and gap junctions (green) are heterogeneously distributed, with additional regions of reduced ion ...
Ena Ivanovic, Marina Vannucci, Nicolae Moise, Seth H. Weinberg, Jan P. Kucera   +4 more
wiley   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source

Panoramic voltage‐sensitive optical mapping of contracting hearts using cooperative multiview motion tracking with 12 cameras

The Journal of Physiology, EarlyView.
Abstact figure legend A panoramic 3D optical mapping system was developed, enabling imaging of action potential waves across the entire strongly deforming ventricular surface of beating isolated hearts. The system comprises 12 high‐speed cameras and a soccerball‐shaped imaging chamber with 48 light‐emitting diodes (LEDs).
Shrey Chowdhary, Jan Lebert, Shai Dickman, Mason Manetta, Charles Gordon, Jan Christoph   +5 more
wiley   +1 more source

Multiscale mechanistic modelling of heterogeneity in cardiac sub‐cellular calcium handling accounting for variable t‐system density

The Journal of Physiology, EarlyView.
Abstract figure legend Illustration of spatial calcium dynamics (left panels) and the state cycle approximation (middle panel) that enables reduced simulation of spatially dependent dynamics without explicit description of space (right panels). The selected example here illustrates a spontaneous calcium wave, showing temporal snapshots of local calcium
Michael A Colman, Yohannes Shiferaw, David Conesa   +2 more
wiley   +1 more source

Atrial Tachycardia Utilizing Bachmann's Bundle as an Epicardial Bypass: A Case Suggestive of a Dual‐Loop Mechanism

Annals of Noninvasive Electrocardiology, Volume 31, Issue 4, July 2026.
The activation propagated in a superior‐to‐inferior direction on the anterior wall and in an inferior‐to‐superior direction on the posterior wall (depicted with a yellow arrow). The activation jumped over the low voltage area on the anterior wall through the epicardial bridge (indicated by a white dotted arrow).
Ryutaro Sakurai, Yosuke Nakatani, Kensuke Fujiwara, Takashi Miyamoto   +3 more
wiley   +1 more source

Global Observational Comparison of Large‐Scale Traveling Atmospheric and Ionospheric Disturbances During the May 2024 Geomagnetic Storm

Geophysical Research Letters, Volume 53, Issue 12, 28 June 2026.
Abstract During the geomagnetic storm on 10 May 2024, neutral density measurements from 14 Tianmu, Swarm, and GRACE‐FO satellites at ∼510 km altitude, combined with total electron content (TEC) observations, enabled the first global observational comparison of large‐scale traveling atmospheric and ionospheric disturbances (LSTADs/TIDs) via snapshots ...
Xiaolong Wei, Guoying Jiang, Yajun Zhu, Yongping Li, Jiangzhao Ai, Tingwei Han, Huijun Le, Aibin Zhang, Jiyao Xu   +8 more
wiley   +1 more source

Retrospective Study Comparing Topography-Guided and Wavefront-Optimized LASIK Procedures in a Single Center

Sheri L Rowen,1 Tom Tooma,1 Ngoc Trieu,1 Brad Hall2 1Nvision Eye Centers, Newport Beach, CA, USA; 2Sengi, Penniac, NB, CanadaCorrespondence: Sheri L Rowen, Nvision Eye Centers, 4220 Von Karman #100, Newport Beach, CA, 92660, USA, Tel +1-877-455-9942,
Rowen SL, Trieu N, Tooma T, Hall B
core  

Dynamic Holographic Display With Multiplexed Dielectric Metasurfaces

Nanophotonics, Volume 15, Issue 12, 25 June 2026.
Based on multiplexed metasurfaces, we show hybrid multiplexing of polarization, wavelength, and orbital angular momentum can be applied for dynamic tuning. Our strategy presents a highly compact and efficient solution for high‐capacity, multi‐dimensional holography, with promising applications in advanced displays, data storage, optical encryption, and
Yu Liu, Yu‐Tong Xiao, Xing‐Yuan Huo, Qing Cai, Rui Zhong, Ling‐Yuan Zhang, Ruwen Peng, Yongmin Liu, Mu Wang   +8 more
wiley   +1 more source