Results 151 to 160 of about 3,906 (246)

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source

Wavefront sensing at X-ray free-electron lasers. [PDF]

J Synchrotron Radiat, 2019
Seaberg M, Cojocaru R, Berujon S, Ziegler E, Jaggi A, Krempasky J, Seiboth F, Aquila A, Liu Y, Sakdinawat A, Lee HJ, Flechsig U, Patthey L, Koch F, Seniutinas G, David C, Zhu D, Mikeš L, Makita M, Koyama T, Mancuso AP, Chapman HN, Vagovič P.   +22 more
europepmc   +1 more source

Panoramic voltage‐sensitive optical mapping of contracting hearts using cooperative multiview motion tracking with 12 cameras

The Journal of Physiology, EarlyView.
Abstact figure legend A panoramic 3D optical mapping system was developed, enabling imaging of action potential waves across the entire strongly deforming ventricular surface of beating isolated hearts. The system comprises 12 high‐speed cameras and a soccerball‐shaped imaging chamber with 48 light‐emitting diodes (LEDs).
Shrey Chowdhary, Jan Lebert, Shai Dickman, Mason Manetta, Charles Gordon, Jan Christoph   +5 more
wiley   +1 more source

Improved Machine Learning Approach for Wavefront Sensing. [PDF]

Sensors (Basel), 2019
Guo H, Xu Y, Li Q, Du S, He D, Wang Q, Huang Y.   +6 more
europepmc   +1 more source

Multiscale mechanistic modelling of heterogeneity in cardiac sub‐cellular calcium handling accounting for variable t‐system density

The Journal of Physiology, EarlyView.
Abstract figure legend Illustration of spatial calcium dynamics (left panels) and the state cycle approximation (middle panel) that enables reduced simulation of spatially dependent dynamics without explicit description of space (right panels). The selected example here illustrates a spontaneous calcium wave, showing temporal snapshots of local calcium
Michael A Colman, Yohannes Shiferaw, David Conesa   +2 more
wiley   +1 more source

Comparative multimodal calibration of patient‐specific atrial fibrillation models: Impact of imaging and electrophysiology data on arrhythmogenic substrate identification

The Journal of Physiology, EarlyView.
Abstract figure legend Comparative multimodal calibration of patient‐specific left atrial (LA) models to identify arrhythmogenic substrates in atrial fibrillation (AF). A, LA models shown in posterior and anterior views, calibrated separately using: late gadolinium enhancement magnetic resonance imaging (LGE‐MRI) image intensity ratio (IIR; blue–red ...
Mahmoud Ehnesh, Haseeb Valli, Ovais A. Jaffery, Sam Coveney, Alexander Zolotarev, Zhong Chen, Wajid Hussain, David G. Jones, Raad Mohiaddin, Tom Wong, Gregory Slabaugh, Steven A. Niederer, Edward Vigmond, Shouvik Haldar, Caroline Roney   +14 more
wiley   +1 more source

Semi‐Automated μCT‐Based Modeling of Vertebral Bony Endplate Microporosity and Mechanical Properties: Linking Microstructure to Inferred Mechanical Performance

JOR SPINE, Volume 9, Issue 3, September 2026.
ABSTRACT Background The vertebral bony endplate (BEP) plays a role in regulating both mechanical load transfer and nutrient transport to the intervertebral disc, functions strongly influenced by its microstructural porosity. Variations in porosity impact bone strength, elasticity, and solute diffusion, affecting its overall mechanical competence ...
Ahmad Alminnawi, Gabriele Nasello, Katherine B. Crump, Benjamin Gantenbein, Jerome Noailly, Liesbet Geris   +5 more
wiley   +1 more source

Metrology for Quantum Hardware Standardization—Charting a Pathway: A Strategic Review

IEEJ Transactions on Electrical and Electronic Engineering, Volume 21, Issue 9, Page 1282-1296, September 2026.
Advances in quantum mechanics have long underpinned metrology by enabling practical realizations of units through quantum effects. With the 2019 SI revision, traceability is anchored in defined fundamental constants, reinforcing the quantum‐mechanical basis of modern standards. In parallel, quantum technologies are transitioning from laboratory science
Nobu‐Hisa Kaneko
wiley   +1 more source

Ultra Compact and Broadband Fiber Facet Graphene Oxide Microlens Array Fabricated on a Beam‐Expanding Fiber Facet Using Femtosecond Laser Direct Writing Technique

Nanophotonics, Volume 15, Issue 15, 13 August 2026.
A 400 nm graphene oxide film on a beam‐expanding fiber facet is patterned by femtosecond laser direct writing into a 19‐lens microlens array. The device simultaneously splits a single input beam into multiple 0.67–0.74 NA focus spots with a broadband response from 850 to 1550 nm.
Xiaoke Chen, Lin Ma, Linbin Bai, Tianqi Cheng, Zuyuan He   +4 more
wiley   +1 more source

Direct wavefront sensing enables functional imaging of infragranular axons and spines. [PDF]

Nat Methods, 2019
Liu R, Li Z, Marvin JS, Kleinfeld D.
europepmc   +1 more source