Results 111 to 120 of about 3,808 (215)

All-fiber architecture for high speed core-selective switch for multicore fibers. [PDF]

open access: yesCommun Eng
Melo C   +8 more
europepmc   +1 more source

Microscopy and spectroscopy approaches to study GPCR structure and function

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract The GPCR signalling cascade is a key pathway responsible for the signal transduction of a multitude of physical and chemical stimuli, including light, odorants, neurotransmitters and hormones. Understanding the structural and functional properties of the GPCR cascade requires direct observation of signalling processes in high spatial and ...
Tomáš Fessl   +2 more
wiley   +1 more source

Edge-guided inverse design of digital metamaterial-based mode multiplexers for high-capacity multi-dimensional optical interconnect. [PDF]

open access: yesNat Commun
Sun A   +19 more
europepmc   +1 more source

Upregulation of YY1/EZH2 and MLH1 as Therapeutic Targets for Adult T‐Cell Leukemia/Lymphoma

open access: yesCancer Science, EarlyView.
UMAP projection of CD4 T cells from ATLL patients specified a CD48‐deficient cluster, in which YY1 and EZH2 are upregulated. ABSTRACT The clinical and genetic presentation of adult T‐cell leukemia/lymphoma (ATLL) ranges from indolent to aggressive, making it difficult to identify common therapeutic targets.
Takuya Shimizu   +5 more
wiley   +1 more source

Real‐Time Rendering Framework for Holography

open access: yesComputer Graphics Forum, EarlyView.
Abstract With the advent of holographic near‐eye displays, the need for rendering algorithms that output holograms instead of color images emerged. These holograms usually encode phase maps that alter the phase of coherent light sources such that images result from diffraction effects.
Sascha Fricke   +3 more
wiley   +1 more source

TREM2 Impedes Recovery After Spinal Cord Injury by Regulating Microglial Lysosomal Membrane Permeabilization‐Mediated Autophagy

open access: yesCell Proliferation, EarlyView.
TREM2 exacerbates spinal cord injury by inhibiting TFEB nuclear translocation, aggravating lysosomal membrane permeabilisation and consequently suppressing autophagy. ABSTRACT Microglia, considered as the main immune responder, play an important role in regulating neuroinflammation in central nervous system (CNS) disorders. Our previous work found that
Tianlun Zhao   +6 more
wiley   +1 more source

Deciphering the Immunomodulatory Function of GSN+ Inflammatory Cancer‐Associated Fibroblasts in Renal Cell Carcinoma Immunotherapy: Insights From Pan‐Cancer Single‐Cell Landscape and Spatial Transcriptomics Analysis

open access: yesCell Proliferation, EarlyView.
Pan‐cancer scRNA‐seq and ST‐seq analyses identify GSN+ inflammatory cancer‐associated fibroblasts (CAFs) and their spatial distribution in immune checkpoint inhibitor (ICI) therapy. The Caf.Sig model accurately predicts ICI response across cancers using CAF gene signatures and machine learning.
Shan Li   +18 more
wiley   +1 more source

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