Results 41 to 50 of about 3,808 (215)

Colorectal Cancer Cells–Derived Exosomal PIK3CA Mutation DNA Promotes Tumor Metastasis by Activating Fibroblast and Affecting Tumor Metastatic Microenvironment

Advanced Science, EarlyView.
PIK3CAH1047R DNA in colorectal cancer (CRC) cell‐derived exosomes can be delivered into recipient fibroblasts, where it is transcribed and translated, leading to the activation of fibroblasts into cancer‐associated fibroblasts, which secrete elevated levels of IL6. The simultaneous detection and targeting of PIK3CAH1047R mutation and IL6 may serve as a
Rui Wang, Wanming Li, Yuqiong Lv, Wei Ba, Ying Jiang, Xiaoshuai Li, Jin Fang   +6 more
wiley   +1 more source

Multi‐Wavelength Achromatic 3D Meta‐holography with Zoom Function

Advanced Science, EarlyView.
Due to the wavelength mismatch, chromatic aberrations are inevitable in multi‐wavelength meta‐holography. Moreover, since the meta‐hologram is difficult to be refreshed, zoom meta‐holography has not been reported to date. This study proposes a multi‐wavelength achromatic 3D meta‐holography with a zoom function, breaking through both the chromatic ...
Chao Liu, Yi Zheng, Di Wang, Qian Huang, Xiao‐Wei Li, Fan‐Chuan Lin, You‐Ran Zhao, Yi‐Wei Zheng, Xiao‐Ke Lu, Xin‐Ru Li, Xin‐Ru Zheng, Xin Xie, Kun Song, Zhen‐Fei Li, Wei Lu, Din Ping Tsai, Ruo‐Nan Ji, Qiong‐Hua Wang   +17 more
wiley   +1 more source

Radiation Exposure Induced Blood–Brain Barrier Injury via Mitochondria‐Mediated Sterile Inflammation

Advanced Science, EarlyView.
This work describes a blood–brain barrier (BBB) microphysiological system (MPS) to explore the responses of BBB to radiation exposure. Following radiation exposure, obvious BBB comprise and brain endothelial injuries are detected. Mechanism study shows radiation induced significant sterile inflammation via mitochondrial dysfunction and cGAS‐STING ...
Peng Wang, Jiayue Liu, Min Zhang, Juan Yang, Peihan Lian, Xiu Cheng, Jianhua Qin   +6 more
wiley   +1 more source

Time and phase alignment of distributed gateways: Theoretical analysis and experimental demonstration

International Journal of Satellite Communications and Networking, EarlyView., 2023
The performance limitation in multiple‐input multiple‐output (MIMO) feeder links due to time and phase misalignment of the ground stations is investigated. Time and phase distribution over optical fiber is considered as an approach to achieve the synchronization requirements.
Eriserdi Mollaymeri, Thomas Delamotte, Andreas Knopp   +2 more
wiley   +1 more source

Distributed Acoustic Sensor Using a Double Sagnac Interferometer Based on Wavelength Division Multiplexing. [PDF]

Sensors (Basel), 2022
Zhirnov AA, Choban TV, Stepanov KV, Koshelev KI, Chernutsky AO, Pnev AB, Karasik VE.   +6 more
europepmc   +1 more source

A Smart Single‐Loop‐Mediated Isothermal Amplification Facilitates Flexible SNP Probe Design for On‐Site Rapid Differentiation of SARS‐CoV‐2 Omicron Variants

Advanced Science, EarlyView.
The ssLAMP method amplifies the nucleic acid of pathogen and identifies SNP mutations. By combining the portable detection device with smartphone‐based analysis software, enables rapid, on‐site SNP detection and genotyping of SARS‐Cov‐2 Omicron variants, providing a cost‐effective and field‐deployable solution for precise pathogen identification in ...
Qijie Lin, Hongchao Gou, Xiaoyun Qu, Kaiyuan Jia, Yuhui Deng, Dan Li, Qianyi Cai, Yucen Liang, Xiaozhen Xu, Yanbin Li, Jianhan Lin, Letian Li, Yuhang Jiang, Shouwen Du, Lingcong Deng, Bailing Yan, Ruidong Liu, Chang Li, Jianmin Zhang, Ming Liao   +19 more
wiley   +1 more source

Plasmonic Molecular Entrapment for Label‐Free Methylated DNA Detection and Machine‐Learning Assisted Quantification

Advanced Science, EarlyView.
Plasmonic molecular entrapment (PME) is label‐free detection and quantification method for DNA methylation. This technique provides direct hotspot site generation around target analytes, overcoming mismatch geometrical properties. The PME demonstrates superior SERS performance and quantification capability, offering promising potential for epigenetic ...
Muhammad Shalahuddin Al Ja'farawy, Vo Thi Nhat Linh, Chaewon Mun, Jun‐Yeong Yang, Jun Young Kim, Rowoon Park, Sung‐Gyu Park, Dong‐Ho Kim, Min‐Young Lee, Ho Sang Jung   +9 more
wiley   +1 more source

Artificial Intelligent‐Enhanced Metabolite Profiling for Intraoperative IDH1 Genotyping in Glioma Using an Orthogonally Responsive SERS Probe

Advanced Science, EarlyView.
This study presents a novel approach for intraoperative identification of the IDH1 genotype in glioma patients using a surface‐enhanced Raman scattering (SERS) probe to measure glutathione and hydrogen peroxide. By integrating AI‐driven deep learning algorithms, the method achieves rapid and accurate genotype differentiation, offering the potential to ...
Hang Yin, Xin Zhang, Zheng Zhao, Chong Cao, Minhua Xu, Suhongrui Zhou, Tian Xuan, Ziyi Jin, Limei Han, Yang Fan, Cong Wang, Xiao Zhu, Ying Mao, Jinhua Yu, Cong Li   +14 more
wiley   +1 more source

Achromatic 3D Multi‐Color Orbital Angular Momentum Holography

Advanced Science, EarlyView.
This work presents an achromatic 3D multicolor orbital angular momentum (OAM) holography based on spatial multiplexing. By integrating wavelength‐specific lens functions onto monochromatic Fourier OAM‐dependent holograms and high‐resolution spatial discretization and interleaving via two‐photon lithography (TPL), the approach addresses axial chromatic ...
Hang Su, Baoli Li, Yike Bai, Yiqi Ye, Yibo Dong, Xinyuan Fang   +5 more
wiley   +1 more source

36‐Channel Spin and Wavelength Co‐Multiplexed Metasurface Holography by Phase‐Gradient Inverse Design

Advanced Science, EarlyView.
A single‐cell metasurface is designed to multiplex holographic images across both spin and wavelength channels using a single‐phase map. By employing inverse design and automatic differentiation, the metasurface achieves 36 channel multiplexing across the visible to near‐infrared spectrum.
Cherry Park, Youngsun Jeon, Junsuk Rho
wiley   +1 more source