Results 61 to 70 of about 2,732,015 (387)
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source
Generation of pulsed dual wavelength erbium doped fiber laser [PDF]
, 2019 Single and dual wavelength fiber lasers and pulsed fiber lasers are well-known to be used for various applications. In the generation of dual wavelength fiber lasers and pulsed fiber lasers, the researchers found the mode competition among the dual ...
Abdul Hadi, Fatin Shaqira
core
125 Gbit/s discretely tunable InP-on-silicon filtered feedback laser with sub-nanosecond wavelength switching times [PDF]
, 2018 A heterogeneously integrated InP-on-silicon fast tunable filtered feedback laser is demonstrated. The laser device consists of a main Fabry-Pérot cavity connected to an integrated arrayed waveguide grating of which the outputs form external cavities in ...
+3 more
core +2 more sources
Waveguide sub‐wavelength structures: a review of principles and applications
, 2015 Periodic structures with a sub‐wavelength pitch have been known since Hertz conducted his first experiments on the polarization of electromagnetic waves.
R. Halir +10 more
semanticscholar +1 more source
Sub-wavelength grating for enhanced ring resonator biosensor.
Optics Express, 2016 While silicon photonic resonant cavities have been widely investigated for biosensing applications, enhancing their sensitivity and detection limit continues to be an area of active research.
J. Flueckiger +6 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source
Four-Photon Quantum Interferometry at a Telecom Wavelength
, 2011 We report the experimental demonstration of four-photon quantum interference using telecom-wavelength photons. Realization of multi-photon quantum interference is essential to linear optics quantum information processing and measurement-based quantum ...
Hideo Kosaka +5 more
core +1 more source
Ultrafast and bias-free all-optical wavelength conversion using III-V-on-silicon technology [PDF]
, 2011 Using a 7.5 μm diameter disk fabricated with III-V-on-silicon fabrication technology, we demonstrate bias-free all-optical wavelength conversion for non-return-to-zero on–off keyed pseudorandom bit sequence (PRBS) data at the speed of 10 Gbits/s with an ...
Baets, Roel +10 more
core +2 more sources
Quantum teleportation from a telecom-wavelength photon to a solid-state quantum memory [PDF]
Nature Photonics, 2014 Quantum teleportation of the state of a qubit encoded in the polarization state is demonstrated from a telecom-wavelength photon to a solid-state quantum memory via 24.8 km of optical fibre.
F. Bussières +13 more
semanticscholar +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source