Results 61 to 70 of about 892,430 (313)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Wavelength tunable transmitters for future reconfigurable agile optical networks [PDF]
, 2009 Wavelength tuneable transmission is a requirement for future reconfigurable agile optical networks as it enables cost efficient bandwidth distribution and a greater degree of transparency.
Maher, Robert D.
core
Comparison study of algorithms and accuracy in the wavelength scanning interferometry [PDF]
, 2012 Wavelength scanning interferometry (WSI) can be used for surface measurement with discontinuous surface profiles by producing phase shifts without any mechanical scanning process.
Gao, F. +4 more
core +1 more source
Construction of the Mean Sea Surface Model Combined HY-2A With DTU18 MSS in the Antarctic Ocean
Frontiers in Environmental Science, 2021 A new Mean Sea Surface (MSS) model called Shandong University of Science and Technology Antarctic Mean Sea Surface model (SDUST_ANT MSS) in the Antarctic Ocean is presented and validated in this paper. The SDUST_ANT MSS updates the DTU18 MSS with 6 years
Weikang Sun +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Characterization of wavelength interleaving in radio-over-fiber systems employing WDM/SCM [PDF]
, 2006 A radio-over-fiber (RoF) distribution system incorporating both sub-carrier multiplexing and wavelength division multiplexing (WDM) technologies is presented. This signal is directly modulated onto three high-speed lasers.
Anandarajah, Prince M. +3 more
core +1 more source
A conceptual approach to material detection based on damping vibration-force signals via robot
Frontiers in NeuroroboticsIntroductionObject perception, particularly material detection, is predominantly performed through texture recognition, which presents significant limitations. These methods are insufficient to distinguish between different materials with similar surface
Ahmad Saleh Asheghabadi +5 more
doaj +1 more source
Photonics, 2023 Distributed Bragg reflector (DBR) lasers are widely used in many physics experiments. However, regarding the power and frequency control of DBR lasers, obtaining complete and accurate output characteristics is challenging due to the need for general and ...
Ziqian Yue +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Analysis of changes in cotton moisture under the influence of infrared (IR) radiation [PDF]
BIO Web of ConferencesCurrent cotton drying technology has a negative impact on product quality due to the use of high temperatures and very low energy efficiency. In the literature on the research on their elimination, information on heat generation from fuel by traditional ...
Kayumov Abdul-Malik +2 more
doaj +1 more source