Results 61 to 70 of about 1,935,997 (301)

Wavelength dependence of light diffusion in strongly scattering macroporous gallium phosphide [PDF]

, 2008
We present time-resolved measurements of light transport through strongly scattering macroporous gallium phosphide at various vacuum wavelengths between 705 nm and 855 nm.
Lagendijk, A., Mosk, A.P., Peeters, W.H., Vellekoop, I.M.   +3 more
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Ring-resonator-based wavelength filters [PDF]

, 2006
Microring resonators (MR) represent a class of filters with characteristics very similar to those of Fabry–Perot filters. However, they offer the advantage that the injected and reflected signals are separated in individual waveguides, and in addition ...
Driessen, A., Geuzebroek, D.H.
core   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Transcranial Laser Stimulation Research—A New Helmet and First Data from Near Infrared Spectroscopy

Medicines, 2018
This editorial adopts a future-oriented technology. It describes a new modern helmet for transcranial laser stimulation and a way to quantify effects of this possible therapeutical method using near-infrared spectroscopy.
Gerhard Litscher
doaj   +1 more source

Wavelength of Experimental LEDS: Hardness, Elastic Modulus, Degree of Conversion and Temperature Rise of a Microhybrid Composite [PDF]

Materials Research, 2015
The aim of this study was to evaluate the effect of different peak wavelengths (450nm, 468nm and 490nm) of experimental LEDs on hardness, elastic modulus, degree of conversion and temperature rise of a microhybrid resin composite – Venus® (Heraeus Kulzer)
Ana Paula Bonilauri Ferreira, Paulo César Soares Júnior, Evelise Machado Souza, Rodrigo Nunes Rached, Sérgio Henrique Pezzin, Sérgio Vieira   +5 more
doaj   +1 more source

Cross talk penalty in two-channel wavelength conversion by four-wave mixing in a strained semiconductor optical amplifier [PDF]

, 1997
A crucial function in wavelength-division multiplexed (WDM) all-optical networks is a wavelength converter. This function enhances wavelength routing options and improves network reconfigurability.
Geraghty, David F., Hedekvist, Per Olof, Koren, Uzi, Lee, Robert B., Vahala, Kerry J.   +4 more
core  

Compact graphene mode-locked wavelength-tunable erbium-doped fiber lasers: from all anomalous dispersion towards all normal dispersion

, 2010
Soliton operation and soliton wavelength tuning of erbium-doped fiber lasers mode locked with atomic layer graphene was experimentally investigated under various cavity dispersion conditions.
Akhmediev, B. Lin, Bao, Bao, Chen, D.Y. Tang, Geim, H. Zhang, K.P. Loh, Kong, L.M. Zhao, Lin, Liu, Liu, Luo, Nelson, Newson, Q.L. Bao, S.C. Tjin, Tan, Tang, Wang, Wang, Wise, Xia, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang   +30 more
core   +1 more source