Results 91 to 100 of about 2,053 (246)

The effects of whole-body muscle stimulation on body composition and strength parameters: A protocol for systematic review and meta-analysis [PDF]

, 2021
Background: This study will analyze the effect of Whole Body Electromyostimulation (WB-EMS) in strength and body composition outcomes in adult population.
Adsuar, José Carmelo, Carlos-Vivas, Jorge, Castelli Correia de Campos, F., Gómez-Campos, Rossana, Hernández-Mocholi, MIguel Ángel, Louro, Hugo, Pérez-Gómez, Jorge, Rodrigues-Santana, Luiz   +7 more
core  

Autophagy Activators Normalize Aberrant Tau Proteostasis and Rescue Synapses in Human Familial Alzheimer's Disease iPSC‐Derived Cortical Organoids

Advanced Science, EarlyView.
A new cerebrocortical organoid model using isogenic hiPSCs with familial Alzheimer's mutations recapitulates key AD features, including amyloid‐beta and phospho‐Tau aggregation, neuronal hyperexcitability, and synapse loss. Single‐cell RNA‐seq reveals aberrant pathways in excitatory and inhibitory neurons.
Sergio R. Labra, Jadon Compher, Akhil Prabhavalkar, Mireya Almaraz, Claudia Cedeño Kwong, Christine Baal, Maria Talantova, Nima Dolatabadi, Julian Piña‐Sanz, Yubo Wang, Leonard Yoon, Swagata Ghatak, Zi Gao, Yuting Zhang, Dorit Trudler, Lynee Massey, Wei Lin, Anthony Balistreri, Michael Bula, Nicholas J. Schork, Tony S. Mondala, Steven R. Head, Jeffery W. Kelly, Stuart A. Lipton   +23 more
wiley   +1 more source

Revisión de los beneficios físicos de la electroestimulación integral [PDF]

La electroestimulación integral (WB-EMS) está cobrando gran relevancia debido a la irrupción de esta tecnología en el sector del fitness y a la propagación viral de multitud de centros que ofertan este sistema que promueven una serie de beneficios ...
de la Cámara Serrano, Miguel Ángel
core  

Análise do dano muscular e das respostas cardiometabólicas após eletroestimulação neuromuscular de corpo inteiro em indivíduos idosos [PDF]

, 2020
Introdução: Estudos têm demonstrado que a eletroestimulação neuromuscular de corpo inteiro (WB-EMS) pode produzir respostas fisiológicas positivas e ser uma opção interessante para populações idosas com alguma resistência aos exercícios convencionais. No
Ferrareze, Matheus Elias
core  

The effects of electrical whole body muscle stimulation (WB-EMS) in patients with chronic unspecific back pain

, 2019
The preferred intervention for treating patients with chronic nonspecific back pain, is active resistance training. Whole body Electromyostimulation (WB-EMS) is becoming increasingly popular as efficient training method. Therefore, applying this kind of training seems logical in patients with chronic unspecific back pain.
Konrad, Karl Lorenz, Baeyens, Jean-Pierre, Jansson, Volkmar, Wegener, Bernd   +3 more
openaire   +1 more source

Chloroplast Stress Signals Orchestrate Epidermis‐Specific Remodeling of Mitochondria and ER Under High Light

Advanced Science, EarlyView.
High light exposure triggers an epidermis‐specific remodeling of mitochondria and ER in Arabidopsis, driven by chloroplast‐derived signals. Live‐cell imaging shows that HL rapidly suppresses mitochondrial motility, followed by fusion‐driven elongation and ER cisternal expansion.
Evan R. Angelos, Hee‐Seung Choi, Jingzhe Guo, Andrea A. Zanini, Tessa M. Burch‐Smith, Emily Snyder, Matthew Part, Wilhelmina van de Ven, Manhoi Hur, Gerd Ulrich Balcke, Alain Tissier, Quanqing Zhang, Katayoon Dehesh   +12 more
wiley   +1 more source

Alkaline Phosphatase‐Activated NIR‐II AIEgens Nanosystem for Surgical and Postoperative Closed‐Loop Therapy of Advanced Osteosarcoma

Advanced Science, EarlyView.
This study designed a tumor microenvironment‐responsive AIEgen nanoparticle for near‐infrared photoimmunotherapy, which inhibits primary tumors and metastasis by promoting pyroptosis and suppressing aerobic glycolysis. ABSTRACT In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's ...
Kaiyuan Liu, Ruotong Li, Li Zhang, Hengli Lu, Binhui Yang, Qian Hu, Yining Tao, Haoran Mu, Jing Han, Pengfei Zan, Jiakang Shen, Dongqing Zuo, Hongsheng Wang, Wei Sun, Xingjun Zhu   +14 more
wiley   +1 more source

IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases and is farnesoid X receptor responsive in NASH

Hepatology, EarlyView., 2022
IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases Abstract Background and Aims Pruritus is associated with multiple liver diseases, particularly those with cholestasis, but the mechanism remains incompletely understood.
Jun Xu, Ya Wang, Mina Khoshdeli, Matt Peach, Jen‐Chieh Chuang, Julie Lin, Wen‐Wei Tsai, Sangeetha Mahadevan, Wesley Minto, Lauri Diehl, Ruchi Gupta, Michael Trauner, Keyur Patel, Mazen Noureddin, Kris V. Kowdley, Aliya Gulamhusein, Christopher L. Bowlus, Ryan S. Huss, Robert P. Myers, Chuhan Chung, Andrew N. Billin   +20 more
wiley   +1 more source

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

Advanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying, Hangping Fan, Yunhe Wang, Ruhong Jiang, Dongsheng Cai, Hui Cheng, Hao Wang, Chenyang Jiang, Ping Liang   +8 more
wiley   +1 more source

Wirkeffekte der alternativen Trainingstechnologie Ganzkörper-Elektromyostimulation (WB-EMS) auf chronisch unspezifische Rückenschmerzen [PDF]

, 2020
Background and Aims: The lack of time and, especially for pain patients, a fear of movement (“kinesiophobia”) as well as functional limitations often oppose participation in such activities. In contrast, the advantage of novel training technologies like
Weissenfels, Anja
core   +1 more source