Results 181 to 190 of about 2,053 (246)

Biomolecular Interaction Prediction in the Pre‐ and Post‐AlphaFold Era: The 8th CAPRI Evaluation

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT We report on the 8th CAPRI Evaluation period, capturing the assessment of CAPRI Rounds 47 to 55 (excluding the CASP and COVID‐related Rounds), which have witnessed the transition to AI‐driven prediction tools such as AlphaFold and related alternatives. The prediction Rounds in this evaluation are characterized by a high level of difficulty due
Marc F. Lensink, Nessim Raouraoua, Guillaume Brysbaert, Sameer Velankar, Shoshana J. Wodak, Alexandre M. J. J. Bonvin   +5 more
wiley   +1 more source

Performance of pyDock in 8th CAPRI: Energy‐Based Scoring Applied to Docking and AlphaFold Models

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The 8th CAPRI edition has shown a significant evolution in the field of protein–protein complex structure prediction. We have participated in all 11 targets proposed in this edition, involving domain‐domain, protein–protein, protein‐peptide, and protein‐DNA interactions, including homo‐ and hetero‐meric interfaces.
Luis Angel Rodríguez‐Lumbreras, Mireia Rosell, Miguel Romero‐Durana, Víctor Monteagudo, Fabian Glaser, Juan Fernandez‐Recio   +5 more
wiley   +1 more source

Pharmacological Inhibition of APT2 by Solasonine Promotes Ferroptosis Through Palmitoylation Modulation in Gallbladder Cancer

Phytotherapy Research, EarlyView.
Schematic illustration of SS‐induced ferroptosis through targeting APT2‐mediated STAT3 palmitoylation in GBC cells. ABSTRACT Gallbladder cancer (GBC), the most prevalent and lethal biliary tract malignancy, lacks effective therapeutic strategies. Solasonine (SS), a bioactive steroidal alkaloid derived from Solanum nigrum L, exhibits antitumor activity ...
Liu‐qing Shi, Jing‐wei Zhao, Jia‐yun Zhu, Cheng Zhao, Zi‐yi Yang, Li‐jia Pan, Ben Ma, Zheng‐yu Chen, Zi‐ying Wang, Chun‐jie Li, Shi‐lei Liu, Jia‐wei Mei, Ping Dong   +12 more
wiley   +1 more source

Incorporating environmental DNA metabarcoding for improved benthic biodiversity and habitat mapping

Remote Sensing in Ecology and Conservation, EarlyView.
Seafloor imagery is commonly used to collect information about the distribution of benthic organisms in order to generate habitat and biodiversity maps. Recent advances in genomics (e.g., environmental DNA; eDNA) show potential to complement video surveys for habitat mapping, but there have been few examples testing this.
Rylan J. Command, Shreya Nemani, Benjamin Misiuk, Mehrdad Hajibabaei, Nicole Fahner, Emily Porter, Greg Singer, Beverly McClenaghan, Katleen Robert   +8 more
wiley   +1 more source

Sustainability in Small and Medium‐Sized Enterprises (SME): Integrated Research Framework and Future Research Agenda

Sustainable Development, EarlyView.
ABSTRACT Over the past two decades, the concept of sustainability in the context of small and medium‐sized enterprises (SME) has gained significant attention within both business practice and academic research. This has resulted in a rapid and multidisciplinary proliferation of scholarly literature, which has led to an increasing fragmentation of the ...
Kerem Dalgali, Victor Tiberius, Alexander Brem   +2 more
wiley   +1 more source

Revisiting whole blood transfusion for the massively bleeding patient: The origins of resistance to change. [PDF]

Transfusion
Bloch EM, Jacobs JW, Sachais BS, Ziman A, Cushing M, Cap AP, Gurney JM, Beckett A, Yazer MH, Spinella PC, THOR Network.   +10 more
europepmc   +1 more source

On an Aggregation Theory for Indicators Expressing Behaviors of Complex Systems With an Application to Sustainability

Sustainable Development, EarlyView.
ABSTRACT Certain attributes of large‐scale complex systems are often expressed through sets of indicators. For example, the sustainability of an entity, be it a nation, a city, an energy system, a corporation etc., can be effectively represented by indicators and corresponding data series.
Vassilis S. Kouikoglou, Yannis A. Phillis   +1 more
wiley   +1 more source

Horizons and Challenges: An Overview of Strategies for Circular Economy Education in Schools

Sustainable Development, EarlyView.
ABSTRACT Education is fundamental to preparing future professionals for the transition to a circular economy (CE), and it requires the development of competences from the earliest stages of schooling. Nevertheless, teachers continue to face challenges in integrating the circular economy into classroom practice. This article presents a literature review
Maiara Lais Marcon, Simone Sehnem
wiley   +1 more source

Development and Evaluation of a Novel Curriculum for Whole Blood Transfusion by Paramedics in the Prehospital Environment. [PDF]

West J Emerg Med
Garfinkel E, May R, Margolis A, Cohn E, Colburn S, Grawey T, Levy M.   +6 more
europepmc   +1 more source

Amorphous Hydrogenated Silicon Carbide Interlayers: Chemical, Optical, and Tribological Behavior for Improving Adhesion of Carbon‐Based Films to Ferrous Alloy

Surface and Interface Analysis, EarlyView.
ABSTRACT Diamond‐like carbon thin films have been gaining attention in the last years due to their unique properties, such as low friction coefficient and high wear resistance. However, the lack of adhesion between DLC coatings and ferrous alloys complicates their wider industrial application.
Vanessa Piroli, Michael Cristian Goldbeck, Jennifer Stefani Weber, Felipe Cemin, Bruna Louise Perotti, Carla Daniela Boeira, Fernando Alvarez, Newton Kiyoshi Fukumasu, Antonio Ricardo Zanatta, Alexandre Fassini Michels, Carlos Alejandro Figueroa   +10 more
wiley   +1 more source