Results 61 to 70 of about 130,292 (265)

TPI1 Loss Triggers a Metabolite‐Driven Mitochondrial Redox Vulnerability via the SARM1–cADPR–Ca2+ Axis

Advanced Science, EarlyView.
Metabolite‐driven redox stress governs cancer cell senescence. TPI1 deficiency elevates DHAP, initiating SARM1‐dependent cADPR‐Ca2+ release. Mitochondrial ROS surge subsequently induces DNA damage and senescence, offering a conserved therapeutic target in multiple cancers.
Chunyu Liu, Shun Wu, Chuang Wang, Zirui Zhou, Tianwei Cai, Wen Tao, Shidong Zuo, Chi Zhang, Yuhao Dong, Yi Feng, Qingbo Huang, Baojun Wang, Xin Ma, Haoli Ma, Xu Zhang, Yan Huang   +15 more
wiley   +1 more source

Sportwissenschaft

Deutsche Zeitschrift für Sportmedizin, 2017
Background: Low back pain (LBP) has a high priority in our predominately sedentary society. The aim of this meta-analysis of present data was to evaluate the effect of whole-body electromyostimulation (WB-EMS) on LBP in sedentary older people with ...
Weissenfels A, Teschler M, von Stengel S, Kohl M, Kemmler W   +4 more
doaj   +1 more source

Gap‐Free Information Transfer in 4D‐STEM via Fusion of Complementary Scattering Channels

Advanced Science, EarlyView.
Fused Full‐Field STEM (FF‐STEM) is introduced as a 4D‐STEM imaging modality that combines direct ptychography with tilt‐corrected dark‐field reconstruction in a single acquisition. Fourier‐space fusion using Wiener‐type spectral weighting closes the low‐frequency contrast gap inherent to bright‐field methods, delivering gap‐free, dose‐efficient, near ...
Shengbo You, Georgios Varnavides, Sagar Khavnekar, Nikita Palatkin, Sihan Shao, Mingjian Wu, Daniel Stroppa, Darya Chernikova, Baixu Zhu, Ricardo Egoavil, Stefano Vespucci, Dileep Krishnan, Xingchen Ye, Florian K. M. Schur, Erdmann Spiecker, Philipp Pelz   +15 more
wiley   +1 more source

Effectiveness of whole-body electromyostimulation on knee pain and physical function in knee osteoarthritis: a randomized controlled trial

Scientific Reports
In a randomized, controlled study, whole-body electromyostimulation (WB-EMS) was investigated as a promising alternative treatment technique compared to conventional strength training for the management of knee osteoarthritis (OA). Seventy-two overweight
Stephanie Kast, Wolfgang Kemmler, Frank W. Roemer, Matthias Kohl, Adam G. Culvenor, Ali Mobasheri, Michael Uder, Simon von Stengel   +7 more
doaj   +1 more source

Effects of an Eight-Week Superimposed Submaximal Dynamic Whole-Body Electromyostimulation Training on Strength and Power Parameters of the Leg Muscles: A Randomized Controlled Intervention Study

Frontiers in Physiology, 2018
The purpose of this study was to assess the effects of dynamic superimposed submaximal whole-body electromyostimulation (WB-EMS) training on maximal strength and power parameters of the leg muscles compared with a similar dynamic training without WB-EMS.
Florian Micke, Heinz Kleinöder, Ulrike Dörmann, Nicolas Wirtz, Lars Donath   +4 more
doaj   +1 more source

Whole-Body EMS Superimposed Walking and Nordic Walking on a Treadmill—Determination of Exercise Intensity to Conventional Exercise

, 2022
Electrical muscle stimulation (EMS) is an increasingly popular training method and has become the focus of research in recent years. New EMS devices offer a wide range of mobile applications for whole-body EMS (WB-EMS) training, e.g., the intensification
Verch, Ronald (Dr.), Hadzic, Miralem (Dr.), Stoll, Josefine, Quarmby, Andrew James (M.Sc.), Völler, Heinz (Prof. Dr.)   +4 more
core   +1 more source

QRICH1 Disrupts Endoplasmic Reticulum Homeostasis and Amplifies NF‐κB Signaling in Periodontal Ligament Stem Cells to Exacerbate Diabetic Periodontitis

Advanced Science, EarlyView.
QRICH1 has been established as a key factor contributing to impaired osteogenic potential and accelerated apoptosis of PDLSCs in diabetic periodontitis. QRICH1 not only significantly enhances UPR‐associated apoptotic signaling but also amplifies NF‐κB‐mediated inflammatory responses. Its inhibition restores osteogenic capacity and reduces alveolar bone
Han Li, Xiaoyu Yang, He Wang, Yunchun Kuang, Yiyao Hu, Houxuan Li, Shuhong Li, Deping Zeng, Jie Li, Jinlin Song   +9 more
wiley   +1 more source

Acute Effects of WB-EMS on 20-min Rowing Time Trial Performance: Randomized Crossover Study

, 2023
Whole-body electromyostimulation (WB-EMS) training is effective in improving training adaptations and recovery. However, WB-EMS is associated with potential side effects and contraindications that can lead to excessive muscle damage and physiological impairment.
Burgos Postigo, Silvia, Recarey, Anel, Fernández Elías, Valentín Emilio   +2 more
openaire   +2 more sources

Engineering‐Modulated Molybdenum Enzymes Strategy for Tumor‐Specific Metabolic‐Immunotherapy

Advanced Science, EarlyView.
Biodegradable molybdenum sulfide nanoparticles were synthesized via a one‐pot strategy to increase molybdenum enzyme activity and thus effectively potentiate anti‐tumor immunity by integrating molybdenum‐based metalloimmunotherapy with hydrogen sulfide gas therapy.
Xiaoxiao Pan, Zifan Pei, Jie Wu, Nan Jiang, Qian Li, Yuqi Yang, Jie Cao, Yechen Huang, Shumin Sun, Qialu Du, Zhicheng Liu, Lin Zhang, Fei Gong, Jinhua Zhou, Liang Cheng   +14 more
wiley   +1 more source

Eficacia de la combinación de Whole-Body Electrical Myostimulation (WB-EMS) con ejercicios de estabilización en pacientes con dolor lumbar crónico inespecífico. Una propuesta de ensayo clínico. [PDF]

, 2022
Introducción: El dolor lumbar crónico inespecífico (DLCI) es una de las causas más comunes de visita al médico. Existen diversos tratamientos y una nueva corriente es el Whole-Body Electrical Myostimulation (WB-EMS).
Andrés Ayala, Rocío
core   +1 more source