Results 51 to 60 of about 69,895 (322)

Effect of Ni content on mechanical properties and corrosion resistance of WC-Co-Ni cemented carbides [PDF]

open access: yesProcessing and Application of Ceramics
WC-Co-Ni cemented carbides with 90 wt.% WC and different Co/Ni ratios (WC-(1−x)Co-xNi, where x = 0, 1, 3, 5, 7 and 9 wt.%) were prepared by powder metallurgy method.
Xu Shubo   +6 more
doaj   +1 more source

Focused ion beam tomography of WC-Co cemented carbides [PDF]

open access: yes, 2017
The microstructure of three different grades of WC-Co cemented carbides (hardmetals) has been reconstructed in three dimensions after sequential images obtained by focused ion beam. The three dimensional microstructual parameters are compared against the
Chen, H.   +6 more
core   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Wear characteristics and micro-cutting damage model of cemented carbide by deep cryogenic treatment

open access: yesJournal of Materials Research and Technology
Wear failure of oil drill bits leads to cost increase, and how to improve the abrasion resistance of cemented carbide (WC–Co) drill bits is an urgent problem, and deep cryogenic treatment (DCT) is a feasible method. The effect of DCT time (i.e., 0, 3, 6,
Weiguo Zhang   +5 more
doaj   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Ni-coated graphene nanoplatelets and their application as reinforcements for WC-Co cemented carbides

open access: yesMaterials Research Express, 2020
In the current research, Ni-coated graphene nanoplatelets (Ni-GNPs) were fabricated by electroless Ni plating process. The Co-cemented tungsten carbides (WC-Co) samples doped with Ni-GNPs were obtained by vacuum hot pressing sintering.
Yigao Yuan, Xingxing Xu, Jianguo Zhang
doaj   +1 more source

Toward a better understanding of tool wear effect through a comparison between experiments and SPH numerical modelling of machining hard materials [PDF]

open access: yes, 2009
The aim of this study is to improve the general understanding of tungsten carbide (WC–Co) tool wear under dry machining of the hard-to-cut titanium alloy Ti6Al4V. The chosen approach includes experimental and numerical tests.
Bil   +26 more
core   +7 more sources

Post‐COVID Fatigue Is Associated With Reduced Cortical Thickness After Hospitalization

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuropsychiatric symptoms are among the most prevalent sequelae of COVID‐19, particularly among hospitalized patients. Recent research has identified volumetric brain changes associated with COVID‐19. However, it currently remains poorly understood how brain changes relate to post‐COVID fatigue and cognitive deficits.
Tim J. Hartung   +190 more
wiley   +1 more source

Home - About - Disclaimer - Privacy