Results 51 to 60 of about 71,922 (323)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Effect of Ni content on mechanical properties and corrosion resistance of WC-Co-Ni cemented carbides [PDF]
Processing and Application of CeramicsWC-Co-Ni cemented carbides with 90 wt.% WC and different Co/Ni ratios (WC-(1−x)Co-xNi, where x = 0, 1, 3, 5, 7 and 9 wt.%) were prepared by powder metallurgy method.
Xu Shubo +6 more
doaj +1 more source
Focused ion beam tomography of WC-Co cemented carbides [PDF]
, 2017 The microstructure of three different grades of WC-Co cemented carbides (hardmetals) has been reconstructed in three dimensions after sequential images obtained by focused ion beam. The three dimensional microstructual parameters are compared against the
Chen, H. +6 more
core +2 more sources
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Wear characteristics and micro-cutting damage model of cemented carbide by deep cryogenic treatment
Journal of Materials Research and TechnologyWear failure of oil drill bits leads to cost increase, and how to improve the abrasion resistance of cemented carbide (WC–Co) drill bits is an urgent problem, and deep cryogenic treatment (DCT) is a feasible method. The effect of DCT time (i.e., 0, 3, 6,
Weiguo Zhang +5 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji +13 more
wiley +1 more source
Mechanics and mechanisms of fatigue in a WC-Ni hardmetal and a comparative study with respect to WC-Co hardmetals [PDF]
, 2015 There is a major interest in replacing cobalt binder in hardmetals (cemented carbides) aiming for materials with similar or even improved properties at a lower price.
Coureaux Mustelier, David +5 more
core +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano +11 more
wiley +1 more source
EVOLUTION OF THE WC-Co STRUCTURE, AS THE RESULT OF PRELIMINARY COLD ISOSTATIC PRESSING UP TO 0.3 GPa AND SINTERING [PDF]
, 2018 Investigation of the effect of cold isostatic pressing of WC-Co samples on the density, coercive force, grain size WC, thickness of the Co interlayer and microhardness ...
AKIMOV, Gennadiy +3 more
core
Annals of Clinical and Translational Neurology, EarlyView.Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source