This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao +7 more
wiley +1 more source
Spatial associations for slow musical tempos are revealed by increased stimulus density. [PDF]
Mariconda A +3 more
europepmc +1 more source
A Soft, Flexible Implant for Wireless Photothermal–Pyroelectric Neurostimulation
A replication strategy is used to enlarge the exposed surface area of barium titanate within flexible films with embedded carbon nanotubes, enabling efficient photothermal‐pyroelectric stimulation. Polar crystalline nanosheets show superior performance in guiding neural progenitor cells toward neuronal differentiation.
Jiang Wu +7 more
wiley +1 more source
Flow of Dilute Aqueous Polymer Solutions in a Heterogeneous Porous Medium: Existence Results for Steady and Unsteady Cases. [PDF]
Baranovskii ES, Artemov MA.
europepmc +1 more source
A Critical Time Window of Neocortex Modulation for Remote Fear Memory in Rats and Humans
This study identifies a delayed consolidation window around 18 h after fear learning in the mPFC essential for remote fear memory. VTA dopaminergic input during this window sustains remote memory in rats, while non‐invasive stimulation of homologous human mPFC at the corresponding time selectively weakens remote but not recent fear memory, revealing a ...
Lu Cao +19 more
wiley +1 more source
From intention to action: student and faculty perspectives on private and public campus pro-environmental behavior. [PDF]
Chen X, Huang J, Huang X.
europepmc +1 more source
Charting Endocrine Progenitors Across Species and Organs
Endocrine progenitors give rise to the hormone‐producing cells of the pancreas and intestine. Using single‐cell multiomics and proteomics, this study compares these progenitors across species, systems, and organs, mapping the conserved and species‐specific gene regulatory networks that guide their formation.
Changying Jing +21 more
wiley +1 more source
Antipsychotics and Sleep Architecture: Where Does Lurasidone Fit? [PDF]
Pham B, Siddiq S.
europepmc +1 more source
Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley +1 more source
Diagnosing method conditioned bias in mineral resource estimation using a mutual information and entropy uncertainty indicator. [PDF]
He X, Huang Y, Wu B, Ao Y, Jiao H.
europepmc +1 more source

