Results 31 to 40 of about 613,416 (211)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Spin fluctuations and weak pseudogap behaviors in Na_{0.35}CoO_2:renomarization of band structure [PDF]

open access: yes, 2005
We analyze the normal electronic states of Na$_{0.35}$CoO$_2$ based on the multi-orbital Hubbard model using the FLEX approximation. The fundamental electronic property of this system is drastically changed by the presence or absence of the small hole ...
Kontani, Hiroshi, Yada, Keiji
core   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Large-wavelength instabilities in free-surface Hartmann flow at low magnetic Prandtl numbers

open access: yes, 2008
We study the linear stability of the flow of a viscous electrically conducting capillary fluid on a planar fixed plate in the presence of gravity and a uniform magnetic field. We first confirm that the Squire transformation for MHD is compatible with the
Batchelor   +10 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Does Kirk's Theorem Hold for Multivalued Nonexpansive Mappings?

open access: yesFixed Point Theory and Applications, 2010
Fixed Point Theory for multivalued mappings has many useful applications in Applied Sciences, in particular, in Game Theory and Mathematical Economics.
Domínguez Benavides T, Gavira B
doaj  

Design of novel nanocrack-structured separators and their application in lithium-ion batteries

open access: yes工程科学学报
The separator, which provides an ion transport pathway while preventing short circuits between electrodes, is an essential component of secondary metal batteries and plays a pivotal role in the stable operation of energy storage systems.
Shuo QIN   +3 more
doaj   +1 more source

Disordered Fulde-Ferrel-Larkin-Ovchinnikov State in d-wave Superconductors

open access: yes, 2009
We study the Fulde-Ferrel-Larkin-Ovchinnikov (FFLO) superconducting state in the disordered systems. We analyze the microscopic model, in which the d-wave superconductivity is stabilized near the antiferromagnetic quantum critical point, and investigate ...
Agterberg D F   +7 more
core   +1 more source

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