Results 81 to 90 of about 3,721,262 (281)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

A framework for measuring weak values without weak interactions and its diagrammatic representation

open access: yesNew Journal of Physics, 2019
Weak values are typically obtained experimentally by performing weak measurements, which involve weak interactions between the measured system and a probe.
Kazuhisa Ogawa   +4 more
doaj   +1 more source

OPERATOR WEAK VALUES AND BLACK HOLE COMPLEMENTARITY [PDF]

open access: yes, 1995
In conventional field theories, the emission of Hawking radiation in the background of a collapsing star requires transplanckian energy fluctuations.
Englert, F.
core   +1 more source

Weak values as interference phenomena

open access: yesPhysical Review A, 2015
16 pages, 4 figures, lots of references; v2 considerably expanded for pedagogical clarity; v3 minor typos ...
openaire   +4 more sources

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

open access: yes
Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra   +9 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Weak Values and Consistent Histories in Quantum Theory

open access: yes, 2003
A relation is obtained between weak values of quantum observables and the consistency criterion for histories of quantum events. It is shown that ``strange'' weak values for projection operators (such as values less than zero) always correspond to ...
Kastner, R. E.
core   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Quantum Measurement and Weak Values in Entropic Dynamics

open access: yes, 2017
The problem of measurement in quantum mechanics is studied within the Entropic Dynamics framework. We discuss von Neumann and Weak measurements, wavefunction collapse, and Weak Values as examples of bayesian and entropic inference.Comment: Presented at ...
Caticha, Ariel, Vanslette, Kevin
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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