Results 61 to 70 of about 40,799 (281)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
SIFAT-SIFAT PEMETAAN OCCASIONALLY WEAKLY COMPATIBLE PADA RUANG METRIK FUZZY [PDF]
, 2017 Penelitian ini bertujuan untuk: (1) menjelaskan pemetaan occasionally weakly compatible pada ruang metrik fuzzy, (2) mengetahui sifat-sifat pemetaan occasionally weakly compatible pada ruang metrik fuzzy ditinjau dari teori titik tetap.
RIZKI, CITRA
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Fixed Point for Weakly Compatible Maps Satisfying Generalized Contraction Principle
, 2011 We prove common fixed point theorems for a pair of weakly compatible mappings satisfying a generalized contraction principle by using a control function and implicit relation.
M. L. Joshi, J. Mehta
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
On Some Generalizations of Commuting Mappings
Abstract and Applied Analysis, 2012 It is shown that occasionally JH operators as well as occasionally weakly biased mappings reduce to weakly compatible mappings in the presence of a unique point of coincidence (and a unique common fixed point) of the given maps.
Mohammad Ali Alghamdi +2 more
doaj +1 more source
Fixed Point Results of Expansive Mappings in Metric Spaces
Mathematics, 2020 In this study, we introduce the concept of θ-expansive mapping in ordered metric spaces and prove a fixed point theorem for such mappings. We give some fixed point results for θ-expansive mapping in metric spaces and prove fixed point theorems for such ...
Seher Sultan Yeşilkaya, Cafer Aydın
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Fixed point and periodic point theorems in fuzzy metric space [PDF]
Songklanakarin Journal of Science and Technology (SJST), 2015 In this paper we prove a periodic point theorem in fuzzy metric space and present some common fixed point theorems for occasionally weakly compatible mappings in fuzzy 3- metric spaces under various conditions.
Binod Chandra Tripathy +2 more
doaj
Quartets in maximal weakly compatible split systems
, 2019 Weakly compatible split systems are a generalization of unrooted evolutionary trees and are commonly used to display reticulate evolution or ambiguity in biological data. They are collections of bipartitions of a finite set X of taxa (e.g.
Koolen, JH, Lee, WS, Grunewald, S
core +1 more source