Results 101 to 110 of about 1,392,301 (300)
Central cord syndrome in the field: Case report [PDF]
ABC: časopis urgentne medicine, 2016 INTRODUCTION: Central syndrome medulla (Central cord syndrome, Sy Schneider, CCS) is a violation of the central part of gray matter and white matter medial part of the cervical spinal cord. Described by Schneider in 1954 godine. It is actually Incomplete
Vukoje Vesna, Milivojević Snežana
doaj
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Fragile States, Robust Structures: Illegal Police Protection in Buenos Aires [PDF]
Weakness is a quality frequently ascribed to Latin American states. This diagnosis proves faulty since it is possible to find resistant structures inside those states that perpetuate such weaknesses. This article shows that this is the case in regards to
Matías Dewey
core
The turning points of EU cohesion policy, Working Paper Report to Barca Report [PDF]
, 2009 In more recent discussions on the future of Cohesion policy, however, both critics and supporters have tended to agree on the need for a “modernisation” of the policy, in recognition of existing weakness in the current approach and of the emerging ...
Manzella, GP, Mendez, Carlos
core
, 2010 We investigate the effect of the intrinsic spin of a fundamental spinor field on the surrounding spacetime geometry. We show that despite the lack of a rotating stress-energy source (and despite claims to the contrary) the intrinsic spin of a spin-half ...
Andrew Randono +6 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
INDIVIDUAL DELIBERATION, MORAL AUTONOMY AND EMOTIONS : ROUSSEAU ON CITIZENSHIP [PDF]
The present study addresses the question of uncertainty in individual deliberation in Rousseau's philosophy. Accordingly, it intends to consider in a new light his account of virtue and citizenship which cannot possibly be defined as systematic obedience
Christophe Salvat
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Reason, Irrationality and Akrasia (Weakness of the Will) in Buddhism: Reflections upon Śāntideva's Arguments with Himself [PDF]
, 2018 Let it be granted that Buddhism has, e.g., in its logical literature, detailed canons and explicit rules of right reason that, amongst other things, ban inconsistency as irrational.
Tillemans, Tom
core