Results 81 to 90 of about 4,523,614 (268)

Early Weaning Stress Induces Chronic Functional Diarrhea, Intestinal Barrier Defects, and Increased Mast Cell Activity in a Porcine Model of Early Life Adversity

Neurogastroenterology and Motility, 2017
Early life adversity (ELA) is a risk factor for development of gastrointestinal disorders later in life. The underlying mechanisms through which ELA and sex interact to influence disease susceptibility remains poorly understood.
Calvin S. Pohl, J. E. Medland, Emily Mackey, Laura L. Edwards, Kristen Bagley, Morgan P. DeWilde, Kurt J. Williams, A. Moeser   +7 more
semanticscholar   +1 more source

Protective Effects of Smilax glabra Roxb. Against Lead-Induced Renal Oxidative Stress, Inflammation and Apoptosis in Weaning Rats and HEK-293 Cells

Frontiers in Pharmacology, 2020
Lead (Pb) is an important environmental pollutant. Oxidative stress and the inflammatory response have been postulated as mechanisms involved in lead-induced renal damage. Smilax glabra Roxb.
Yueyue Shi, Chongmei Tian, Xin-fen Yu, Yuejuan Fang, Xinyu Zhao, Xiaoxi Zhang, Daozong Xia   +6 more
semanticscholar   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Role of soft tissue and bone interactions in the developmental integration and modularity of the skull in neural crest‐specific gap junction alpha‐1 knockout mice

The Anatomical Record, EarlyView.
Abstract The vertebrate skull is composed of bones derived from neural crest cells and mesoderm. The evolutionary capacity of the skull has been linked, in part, to the emergence of neural crest cells; however, this increased capacity for evolutionary change requires that variation within neural crest‐ and mesoderm‐derived bones remains partly ...
Alyssa C. Moore, Madeline Tourigny, Diana Quinonez, Kevin Barr, Matthew W. Grol, Katherine E. Willmore   +5 more
wiley   +1 more source

Dietary Isatidis Root Residue Improves Diarrhea and Intestinal Function in Weaned Piglets

Animals
Weaning stress can trigger diarrhea, cause intestinal damage, and disrupt the intestinal flora of piglets, ultimately resulting in retarded growth or even the death of the animals.
Zhong Chen, Zenghao Yan, Siting Xia, Kaijun Wang, Qi Han, Miao Zhou, Deqin Wang, Jie Yin, Yulong Yin   +8 more
doaj   +1 more source

Effect of Early Weaning on the Intestinal Microbiota and Expression of Genes Related to Barrier Function in Lambs

Frontiers in Microbiology, 2018
Weaning stress has been reported to impair intestinal health. The gut microbiota plays a vital role in the long-term health of the host. However, our understanding of weaning stress on gut microbiota and barrier function is very limited in livestock ...
Chong Li, Chong Li, Weimin Wang, Ting Liu, Qian Zhang, Guoxiu Wang, Fadi Li, Fadi Li, Fadi Li, Fei Li, Xiangpeng Yue, Tingfu Li, Tingfu Li   +12 more
doaj   +1 more source

Early socialization and environmental enrichment of lactating piglets affects the caecal microbiota and metabolomic response after weaning

Scientific Reports, 2021
The aim of this study was to determine the possible impact of early socialization and an enriched neonatal environment to improve adaptation of piglets to weaning. We hypothesized that changes in the microbiota colonization process and in their metabolic
M. Saladrigas-García, M. D’Angelo, H. L. Ko, S. Traserra, P. Nolis, Y. Ramayo-Caldas, J. M. Folch, P. Vergara, P. Llonch, J. F. Pérez, S. M. Martín-Orúe   +10 more
doaj   +1 more source

iTRAQ-based quantitative proteomic analysis of alterations in the intestine of Hu sheep under weaning stress

PLoS ONE, 2018
When Lambs are weaned off ewe’s milk, metabolic, structural, and functional changes often occur in the small intestine. Because information on the effects of weaning stress on the proteome of the intestine is limited, an animal model was established with
K. Cui, Bo Wang, Naifeng Zhang, Y. Tu, T. Ma, Q. Diao   +5 more
semanticscholar   +1 more source

MicroRNA-206 Regulates Stress-Provoked Aggressive Behaviors in Post-weaning Social Isolation Mice

Molecular Therapy: Nucleic Acids, 2020
When facing stressful conditions, some people tend to be impulsively aggressive whereas others are not. However, the causes and underlying mechanisms remain elusive.
Chih-Hua Chang, Elizabeth Joo Wen Kuek, Chun-Lin Su, P. Gean   +3 more
semanticscholar   +1 more source

Developmental differences in cortical bone structure in chimpanzee and human femora reflect early locomotor independence in humans

The Anatomical Record, EarlyView.
Abstract The cortical bone structure of long bone diaphyses changes throughout growth via skeletal modeling and has important implications for bone strength and structural integrity. Ontogenetic trends in diaphyseal structure have been identified in both chimpanzees and humans but it is not yet clear how these trends compare given notable differences ...
Karen R. Swan, Rachel Ives, Zewdi J. Tsegai, Louise T. Humphrey   +3 more
wiley   +1 more source