Results 61 to 70 of about 262,795 (349)

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

Advanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang, Siqi Mu, Juan Zhang, Guisong Shan, Xueqian Li, Ran Wang, Tao Guo, Xiaoyan He   +7 more
wiley   +1 more source

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

Advanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang, Shipeng Dai, Yuchen Xie, Pengyu Chen, Yue Chai, Chongyu Wang, Xueying Huang, Xiao Dong, Junfeng Shi, Yongxiang Xia, Xiaofeng Qian, Weiwei Tang, Yichan Zhou   +12 more
wiley   +1 more source

Selective Confinement by a COF‐Derived Sub‐Nanoporous Interface for High‐Performance CoF2 Thermal Battery Cathodes

Advanced Science, EarlyView.
Dissolution and shuttling of TMF cathodes hinders high‐voltage thermal batteries. A novel selective confinement strategy using a sub‐nanoporous COF‐derived carbon interface (0.54 nm pores) on CoF2 suppresses cathode material shuttling. Size‐selective confinement blocks large dissolved ions (∼0.8 nm) while allowing Li⁺ passage, enhancing thermal battery
Mengfan Xu, Jun Zhang, Lili Zhao, Ying Chu, Furui Luo, Xinping Cao, Shengnan Guo, Xueying Wang, Yongping Zhu, Song Wang   +9 more
wiley   +1 more source

Research on Dynamic Target Search for Multi-UAV Based on Cooperative Coevolution Motion-Encoded Particle Swarm Optimization

Applied Sciences
Effectively strategizing the trajectories of multiple Unmanned Aerial Vehicles (UAVs) within a dynamic environment to optimize the search for and tracking of mobile targets presents a formidable challenge.
Yiyuan Li, Weiyi Chen, Bing Fu, Zhonghong Wu, Lingjun Hao, Guang Yang   +5 more
doaj   +1 more source

Modulation of Network Plasticity Opens Novel Therapeutic Possibilities in Cancer, Diabetes, and Neurodegeneration

Advanced Science, EarlyView.
Plasticity changes of molecular networks form a cellular learning process. Signaling network plasticity promotes cancer, metastasis, and drug resistance development. 55 plasticity‐related cancer drug targets are listed (20 having already approved drugs, 9 investigational drugs, and 26 being drug target candidates).
Márk Kerestély, István Narozsny, Levente Szarka, Daniel V. Veres, Peter Csermely, Dávid Keresztes   +5 more
wiley   +1 more source

An Improved Method for Predicting the Remaining Useful Life Using a Spatial–Temporal Feature Extraction Network With Attention Mechanism

IEEE Access
The prediction of the remaining useful life (RUL) of mechanical equipment is of vital importance to its operation and maintenance. Deep learning methods can effectively extract degradation information closely related to equipment RUL from extensive ...
Xiaojia Yan, Weige Liang, Shiyan Sun
doaj   +1 more source

Quasi‐Antipolar Nanoclusters Driven Superior Energy Storage in High‐Entropy Relaxor Ferroelectrics

Advanced Science, EarlyView.
Quasi‐antipolar nanoclusters are engineered in lead‐free NaNbO3‐based high‐entropy relaxors that weaken polar nanoregion coupling and induce distinct ferroelectric transition under high fields to enable desirable polarization response. This breakthrough system achieves ultrahigh recoverable‐energy‐density (≈18.3 J cm−3), efficiency (≈91.5%), and ...
Ao Tian, Zehao Li, Qingkang Jiang, Xiang Wu, Xuewen Jiang, Xin Gao, Xiaokuo Er, Mohamed Mahmoud, Maqbool Ur Rehman, Liqiang Liu, Aiwen Xie, Tengfei Hu, Ruzhong Zuo   +12 more
wiley   +1 more source

The effect of training interventions on the shooting performance of military and sports fields: A systematic review and meta-analysis [PDF]

فصلنامه ابن سینا, 2023
Background and aims: Shooting plays an important role among the acquired skills of soldiers and is considered one of the main criteria for measuring their capabilities.
Esmail Karami, Hossein Radfar, Javad Eshaghi, Hamed Zarei   +3 more
doaj  

Impact of Secondary Prevention on Mortality in the Building Trades National Medical Screening Program: Effectiveness of Occupational High‐Risk Management

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Since 1997 the Building Trades National Medical Screening Program (BTMed) has offered medical exams to construction workers employed in US nuclear weapons facilities. The process consists of two steps: (1) a detailed work history interview; and (2) a medical exam.
Knut Ringen, John M. Dement, Marianne Cloeren, Sammy Almashat, William Grier, Stella Hines, Laura S. Welch, Kim Cranford, Scott Haas, Patricia Quinn, Anna Chen, Miles Fisher   +11 more
wiley   +1 more source

Factors affecting the accuracy and performance of shooting in both military and sports fields: A review of the literature [PDF]

فصلنامه ابن سینا, 2023
Background and aims: Shooting plays an important role among acquired skills and is considered one of the main criteria for assessing ability. This comprehensive review aimed to summarize the effective and key factors on the accuracy and performance of ...
Esmail Karami, Hossein Radfar, Hamed Zarei   +2 more
doaj