Results 31 to 40 of about 85,461 (258)
From Code to Life: The AI‐Driven Revolution in Genome Editing
Advanced Science, EarlyView.This review explores AI‐driven advancements in genome editing, focusing on CRISPR optimization, enhanced targeting precision, reduced off‐target effects, and novel tool design. It addresses ethical challenges, data biases, and highlights future prospects in precision medicine, agriculture, and synthetic biology.
Zhidong Li +10 more
wiley +1 more source
Analysis of the Magnus Moment Aerodynamic Characteristics of Rotating Missiles at High Altitudes
International Journal of Aerospace Engineering, 2021 The Magnus moment characteristics of rotating missiles with Mach numbers of 1.3 and 1.5 at different altitudes and angles of attack were numerically simulated based on the transition SST model.
Yihang Xu, Shaosong Chen, Hang Zhou
doaj +1 more source
Advanced Science, EarlyView.A novel nanolayered manganese oxide material (Na‐NLMO) is prepared using a rapid and straightforward method for efficient adsorption of Sr(II) in both simulated waste liquid and natural water systems. Its excellent adsorption performance of Na‐NLMO could be attributed to the accessible layered structure and negatively charged framework.
Fan Wang +13 more
wiley +1 more source
Radar Error Correction Method Based on Improved Sparrow Search Algorithm
Applied SciencesAiming at the problem of the limited application range and low accuracy of existing radar calibration methods, this paper studies the radar calibration method based on cooperative targets, and establishes the integrated radar measurement error model ...
Yifei Liu +3 more
doaj +1 more source
A Phase‐Separated SR Protein Reprograms Host Pre‐mRNA Splicing to Enhance Disease Susceptibility
Advanced Science, EarlyView.This study identifies SR30, a splicing factor, as a negative regulator of tomato immunity. During Phytophthora infestans infection, the elevated SR30 forms nuclear condensates to suppress the alternative splicing (AS) of defense‐related genes in a phase separation manner.
Dong Yan +11 more
wiley +1 more source
Advanced Science, EarlyView.The bacterial Type VI secretion system (T6SS) emerges as a sophisticated virulence mechanism, leveraging the dual‐function effector TkeA from Yersinia pseudotuberculosis. TkeA concurrently damages rival bacteria and host cell DNA, triggering the host's cGAS‐STING‐TNF pathway and inducing apoptosis.
Li Song +13 more
wiley +1 more source
Advanced Science, EarlyView.Zheng et al. designed a tumor microenvironment (TME)‐responsive nanosystem, HmBMH@MSA‐2. It targets tumors, releases MSA‐2 and Mn ions in high glutathione (GSH) conditions, achieving STING agonist delivery and MRI. The nanosystem promotes chemodynamic therapy (CDT), achieves radiosensitization, and activates the cGAS‐STING pathway.
Yinfei Zheng +11 more
wiley +1 more source
Case Studies in Thermal Engineering, 2022 Conventional electric heating methods applied when evaluating the natural convection heat transfer parameters at the outer walls of cylinders produce uneven heat flows and large measurement errors.
Qijin Zhao +6 more
doaj
Advanced Science, EarlyView.The PTA‐SnS2@GOx cascade nanosystem presents a smart paradigm for cancer theranostics, integrating self‐supplied H2S/H2O2‐augmented chemodynamic therapy (CDT) with sensitized immunotherapy. Its needle‐like SnS2 shell enhances tumor‐specific uptake, ensuring biosafety.
Xiaoxiao Sun +3 more
wiley +1 more source