Results 51 to 60 of about 8,532,514 (257)

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Development of a novel forward dynamic programming method for weather routing [PDF]

open access: yes, 2012
This paper presents a novel forward dynamic programming method for weather routing to minimise ship fuel consumption during a voyage. Compared with traditional weather routing methods which only optimise the ship's heading, while the engine power or ...
Shao, Wei, Thong, Sew Kait, Zhou, Peilin
core   +4 more sources

Trends of myocardial infarction morbidity and its associations with weather conditions

open access: yesMedicina, 2014
Objective: The aim of this study was to assess the trends of myocardial infarction (MI) morbidity and evaluate the associations with some meteorological factors.
Ričardas Radišauskas   +5 more
doaj   +1 more source

Inventory of Unpublished Climatological Tabulations: Section 4. Summaries of General Weather Conditions, Ceiling Heights, and Visibilities, Monthly and Annual.

open access: yes, 1954
This report outlines weather conditions in 300 hundred stations in the United States, Canada, and Pacific Islands in four figures: (1) Monthly General Weather Conditions, (2) Monthly Ceiling Heights, (3) Monthly Visibility, and (4) Annual Summaries of ...
United States. Department of Commerce.
core  

Modeling Progressive Brain Volume Losses in Chronic Moderate Severe Traumatic Brain Injury: Extensive, but Attenuating

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progressive brain atrophy has now been widely observed in the chronic stages of moderate–severe traumatic brain injury (msTBI), but there is only coarse information regarding its prevalence and magnitude, and whether rate of atrophy accelerates or attenuates across time. We examined these questions in a Canadian inception cohort from
Robin E. A. Green   +6 more
wiley   +1 more source

Significant influence of biometeorological conditions on the incidence of spontaneous pneumothorax in the Kragujevac city [PDF]

open access: yesMedicinski Glasnik, 2011
Aim To explore and establish an influence of biometeorological conditions on the occurrence of spontaneous pneumothorax (SP) in the city of Kragujevac (Serbia) in a five-year period.
Marko Spasić   +4 more
doaj  

Storm Data and Unusual Weather Phenomena

open access: yes, 1959
Monthly report containing a chronological listing, by state, of hurricanes, tornadoes, thunderstorms, hail, floods, drought conditions, lightning, high winds, snow, temperature extremes and other weather phenomena.
United States. Weather Bureau.
core  

Subjective Cognitive Concerns and Cognitive Trajectories in Parkinson's Disease: Biomarker Impact

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the relationship of subjective cognitive concerns (SCC) with biomarkers of Alzheimer's disease (AD), neurodegeneration, and Parkinson's disease (PD) and domain‐specific cognitive trajectories among cognitively unimpaired persons with de novo PD. Method Cognitively unimpaired participants with SCC (n = 294) and without SCC (
Francesca V. Lopez   +5 more
wiley   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley   +1 more source

Objective Quality Evaluation of Images Affected by Adverse Weather Conditions

open access: yesIEEE Access
Recently, there has been a surge in algorithms aimed at improving the perceptual quality of images degraded by adverse weather conditions such as snow, haze, and rain.
Ambreen Bashir   +2 more
doaj   +1 more source

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