Results 41 to 50 of about 1,238,750 (265)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Key Management Systems at the Cloud Scale

open access: yesCryptography, 2019
This paper describes a cloud-scale encryption system. It discusses the constraints that shaped the design of Amazon Web Services’ Key Management Service, and in particular, the challenges that arise from using a standard mode of operation such as ...
Matthew Campagna, Shay Gueron
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Smartphone e GNSS per l'utilizzo professionale

open access: yesGEOmedia, 2017
Smartphones and tablets are nowadays more and more complex, and almost all of them include GNSS modules and other sensors for user localization. After the start of Galileo positioning services, the final positioning quality from mobile devices is ...
Mattia DeAgostino   +4 more
doaj   +2 more sources

Shared Protentions in Multi-Agent Active Inference

open access: yesEntropy
In this paper, we unite concepts from Husserlian phenomenology, the active inference framework in theoretical biology, and category theory in mathematics to develop a comprehensive framework for understanding social action premised on shared goals.
Mahault Albarracin   +5 more
doaj   +1 more source

Visor de Realidad Aumentada en Museos (RAM) para Exposiciones Situadas en Entornos Cerrados

open access: yesVirtual Archaeology Review, 2011
Augmented reality has been increasingly used for the last 10 years. Real and virtual world combination supported by this technology has made augmented reality become an essential element for computer generated data integration in real-world.
Mariano Flores Gutiérrez   +5 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

open access: yesFEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav   +4 more
wiley   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

open access: yesFEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt   +2 more
wiley   +1 more source

JudaicaLink: A Knowledge Base for Jewish Culture and History

open access: yesUmanistica Digitale, 2019
JudaicaLink is a novel resource which provides a knowledge base of Jewish culture and history. It is based on multilingual domain-specific information from encyclopedias and general-purpose knowledge bases such as The Integrated Authority File (GND) of ...
Kay Eckert, Maral Dadvar
doaj   +1 more source

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