Results 31 to 40 of about 101,894 (236)

An accessible Brno city centre for people with impaired mobility

open access: yesJournal of Maps, 2018
Accessibility mapping is an emerging initiative across the world since people with impaired mobility are becoming more and more integrated into mainstream society.
Jana Stehlíková, Tomáš Řezník
doaj   +1 more source

Accessible Learning Management System (LMS) for Disabled People: Project Development Based on Accessibility Guidelines, Gamification, and Design Thinking Strategies

open access: yesThe Role of Gamification in Software Development Lifecycle, 2021
We live in a time of expansion and popularization of the processes of acquisition, retention, and sharing of knowledge in virtual media. Platforms geared towards digital learning now play a fundamental role in mediating knowledge processes.
Leonardo Enrico Schimmelpfeng   +1 more
semanticscholar   +1 more source

Designing an Accountability Index: A Case Study of South America Central Governments

open access: yesCentral European Journal of Public Policy, 2019
The aim of this paper is to evaluate accountability using a newly constructed multivariate accountability index based on the Global Reporting Initiative (GRI), as well as on the accessibility of government disclosure for each country in the South America
Hermosa del Vasto Paola   +3 more
doaj   +1 more source

Community Engagement to Optimize the Use of Web-Based and Wearable Technology in a Cardiovascular Health and Needs Assessment Study: A Mixed Methods Approach

open access: yesJMIR mHealth and uHealth, 2016
BackgroundResource-limited communities in Washington, D.C. have high rates of obesity-related cardiovascular disease in addition to inadequate physical activity (PA) facilities and limited Internet access.
Yingling, Leah R   +14 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

open access: yesFEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki   +11 more
wiley   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

open access: yesFEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng   +13 more
wiley   +1 more source

DEVELOPING AN ONLINE CORPUS OF FORMOSAN LANGUAGES [PDF]

open access: yesTaiwan Journal of Linguistics, 2008
Information technologies have now matured to the point of enabling researchers to create a repository of language resources, especially for those languages facing the crisis of endangerment. The development of an online platform of corpora, made possible
Li-May Sung   +3 more
doaj  

E-Participation: Community Involvement Level Related to Different Services of Local Government Unit Officials

open access: yesInternational Journal of Computing Sciences Research, 2017
Purpose – This paper seeks to answer the level and extent of involvement of the community in the government services to explore how information technologies may work to improve the services to the citizens as an input to e-governance initiative. Method
Francis F. Balahadia   +5 more
doaj   +1 more source

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