Results 91 to 100 of about 4,382,682 (364)

Identifying prognostic targets in metastatic prostate cancer beyond AR

open access: yesFEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng   +13 more
wiley   +1 more source

Web Simplification Prototype for Cognitive Disabled Users

open access: yesHuman Behavior and Emerging Technologies, 2022
Information and communication technology (ICT) and World Wide Web (WWW) are increasingly being used in daily life and becoming important in community, business, personal performance, and improvement of livelihood.
Maira Kamran   +5 more
doaj   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

open access: yesFEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Trends, Prospects and Staffing for Digital Marketing Transformation: from Internet Marketing to MarTech

open access: yesЦифровая трансформация, 2023
The article substantiates the importance of ensuring the efficiency and competitiveness of the websites of Belarusian organizations in the context of the active development of the digital economy and internetization.
I. V. Marakhina, V. A. Parkhimenko
doaj   +1 more source

Most autophagic cell death studies lack evidence of causality

open access: yesFEBS Open Bio, EarlyView.
Of 104 studies claiming autophagic cell death (ACD), only 13 demonstrated both causality and exclusion of apoptosis to confirm true ACD. Most studies relied on correlation‐level data or measured autophagy in isolation, revealing pervasive methodological shortcomings.
Ali Burak Özkaya, Yasmin Ghaseminejad
wiley   +1 more source

DNS weighted footprints for web browsing analytics [PDF]

open access: yesJournal of Network and Computer Applications, 2018
The monetization of the large amount of data that ISPs have of their users is still in early stages. Specifically, the knowledge of the websites that specific users or aggregates of users visit opens new opportunities of business, after the convenient sanitization. However, the construction of accurate DNS-based web-user profiles on large networks is a
García Dorado, José Luis   +3 more
openaire   +3 more sources

From usability to secure computing and back again [PDF]

open access: yes, 2019
Secure multi-party computation (MPC) allows multiple parties to jointly compute the output of a function while preserving the privacy of any individual party’s inputs to that function. As MPC protocols transition from research prototypes to realworld
Albab, Kinan Dak   +7 more
core   +1 more source

A Roadmap for Achieving Privacy in the Age of Analytics: A White Paper from A National Forum on Web Privacy and Web Analytics

open access: yes, 2019
The Montana State University (MSU) Library seeks $100,000 funding from the Institute of Museum and Library Services (IMLS) through its National Forum Grant program under the National Digital Platform project category to hold a meeting around the topics ...
Scott W. H. Young   +3 more
semanticscholar   +1 more source

Statins induce monocytic differentiation in acute myeloid leukemia cells through the KLF4/DPYSL2A axis

open access: yesFEBS Open Bio, EarlyView.
Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura   +7 more
wiley   +1 more source

Инструментарий Google Analytics и его практическое использование в туристическом бизнесе

open access: yesТуризм и гостеприимство, 2016
Статья посвящена анализу инструментария сервиса веб–аналитики Google Analytics и его использованию в туристическом бизнесе. Рассмотрены основные методы веб–анализа и функциональные возможности Google Analytics, направленные на изучение поведения ...
С.А. Демьянов (S.A. Demyanov)
doaj  

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