Results 101 to 110 of about 4,382,682 (364)

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

open access: yesFEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro   +8 more
wiley   +1 more source

Measuring the Online Impact of Your Information Project: A Primer for Practitioners and Funders [PDF]

open access: yes, 2010
Evaluates fifteen Web sites funded by the Knight Foundation's Community Information Challenge, including data on visits, unique visitors, page views, and bounce rates.

core  

Exploring the information behaviour of users of Welsh Newspapers Online through web log analysis [PDF]

open access: yes, 2016
Purpose – Webometric techniques have been applied to many websites and online resources, especially since the launch of Google Analytics (GA). To date, though, there has been little consideration of information behaviour in relation to digitised ...
Gooding, Paul
core   +2 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

How Much is Much?: a Conceptual Study of Web Traffic

open access: yesLiber Quarterly: The Journal of European Research Libraries, 2012
Valid and relevant statistics are required for library planning and advocacy. As libraries and their users turn to the web, library statistics must follow.
Tord Høivik
doaj   +1 more source

Using web analytics tools to assess the effectiveness of means for promoting library resources

open access: yesBibliosphere, 2018
This article is devoted to analysis of the technologies effectiveness to promote library resources. The first part explores using web analytics and its tools in the library.
O. Udartseva, A. E. Rykhtorova
semanticscholar   +1 more source

In Vitro Modeling of Natural Killer Cell Cytotoxicity to Inform Personalized ALS Therapeutics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Natural killer (NK) cells might contribute to motor neuron death in amyotrophic lateral sclerosis (ALS) through direct cytotoxicity, a process that could be inhibited with the FDA‐approved JAK/STAT pathway inhibitor, tofacitinib. This study aimed to verify that tofacitinib can suppress NK cell cytotoxicity, investigate if immune cell
Benjamin J. Murdock   +8 more
wiley   +1 more source

Remaining Burden of Spinal Muscular Atrophy Among Treated Patients: A Survey of Patients and Caregivers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinal muscular atrophy (SMA) significantly impacts motor function. This study aimed to assess the persistent burden and unmet needs among currently treated patients with SMA and their caregivers. Methods Two complementary web‐based surveys were distributed in August 2024 among patients with SMA and their caregivers.
Julie A. Parsons   +8 more
wiley   +1 more source

Data Privacy in Web Analytics - An Empirical Study and Declaration Model of Data Collection on Websites

open access: yesInternational Conference on Web Information Systems and Technologies, 2018
Web analytics has become a useful instrument for electronic business and website management to analyze and optimize website usage. However, different concerns arise in web analytics regarding the collection, storage and usage of web data.
D. Zumstein   +2 more
semanticscholar   +1 more source

Central Dysmyelination in SSADH‐Deficient Humans and Mice

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer   +11 more
wiley   +1 more source

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