Results 41 to 50 of about 386,436 (317)
Application of Web Service in Web Mining
To solve the problems we now encounter in web mining, We first propose a new distributed computing strategy — web service. It suggests building a web mining system based on web service, which can share and manage semi-structured data from heterogeneous platforms.
Beibei Li, Jiajin Le
openaire +1 more source
A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho +7 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
GISClient: la soluzione adatta per la rete
GisClient: the internet GIS solution GisClient is a web applications that allows the management of complex GIS projects, through the use of simple features. In addition to configuring the map, provides powerful tools for managing and analyzing data, all
Davide Caviglia
doaj +2 more sources
Today most of desktop and mobile applications have analogues in the form of web-based applications. With evolution of development technologies and web technologies web application increased in functionality to desktop applications.
V. Solovei, O. Olshevska, Y. Bortsova
doaj +1 more source
Replicating web applications on-demand [PDF]
Many Web-based commercial services deliver their content using Web applications that generate pages dynamically based on user profiles, request parameters etc. The workload of these applications are often characterized by a large number of unique requests and a significant fraction of data updates. Hosting these applications drives the need for systems
Swaminathan Sivasubramanian +2 more
openaire +2 more sources
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
An exponentially increasing of knowledge in a knowledge management system is the main cause of the knowledge overload problem. A development of knowledge recommender service embedded in the knowledge management system becomes a challenging task.
Winyu NIRANATLAMPHONG +1 more
doaj
Background Systems Biology Markup Language (SBML) is the standard model representation and description language in systems biology. Enriching and analysing systems biology models by integrating the multitude of available data, increases the predictive ...
Sascha Schäuble +4 more
doaj +1 more source

