Results 41 to 50 of about 8,665,941 (301)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

THE DIFFERENCE BETWEEN DEVELOPING SINGLE PAGE APPLICATION AND TRADITIONAL WEB APPLICATION BASED ON MECHATRONICS ROBOT LABORATORY ONAFT APPLICATION

open access: yesАвтоматизация технологических и бизнес-процессов, 2018
Today most of desktop and mobile applications have analogues in the form of web-based applications.  With evolution of development technologies and web technologies web application increased in functionality to desktop applications.
V. Solovei, O. Olshevska, Y. Bortsova
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Web Application Development

open access: yes, 2021
Goal of my project is to create a website where users can post their thoughts about wide-range of topics. They can also like and comment on other users' posts which increases user interaction on the website.
Aliyev, Erol
core  

GISClient: la soluzione adatta per la rete

open access: yesGEOmedia, 2009
GisClient: the internet GIS solution GisClient is a web applications that allows the management of complex GIS projects, through the use of simple features. In addition to configuring the map, provides powerful tools for managing and analyzing data, all
Davide Caviglia
doaj   +2 more sources

Hybrid Approach for a Knowledge Recommender Service: A Combination of Item-Based and Tag-Based Recommendation

open access: yesWalailak Journal of Science and Technology, 2017
An exponentially increasing of knowledge in a knowledge management system is the main cause of the knowledge overload problem. A development of knowledge recommender service embedded in the knowledge management system becomes a challenging task.
Winyu NIRANATLAMPHONG   +1 more
doaj  

SBMLmod: a Python-based web application and web service for efficient data integration and model simulation

open access: yesBMC Bioinformatics, 2017
Background Systems Biology Markup Language (SBML) is the standard model representation and description language in systems biology. Enriching and analysing systems biology models by integrating the multitude of available data, increases the predictive ...
Sascha Schäuble   +4 more
doaj   +1 more source

The Diabetes Self-Management Education (DSME) Methods Using Web-Based And Application

open access: yesBabali Nursing Research, 2023
Introduction: Diabetes Self-Management Education (DSME) is a process of providing knowledge to people with diabetes about self-care strategies to optimize metabolic control, prevent complications, and improve the quality of life of people with diabetes.
Gede Satvika Harimahardika   +1 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

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