Results 51 to 60 of about 6,847,953 (291)
Replicating web applications on-demand [PDF]
Many Web-based commercial services deliver their content using Web applications that generate pages dynamically based on user profiles, request parameters etc. The workload of these applications are often characterized by a large number of unique requests and a significant fraction of data updates. Hosting these applications drives the need for systems
Swaminathan Sivasubramanian +2 more
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Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Automatic Parallelisation of Web Applications [PDF]
Small web applications have a tendency to get bigger. Yet despite the current popularity of web applications, little has been done to help programmers to leverage the performance and scalability benefits that can result from the introduction of ...
Perrone, Gian David, Streader, David
core +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
Modern scientific research, conducted on technically complex facilities, often requires auxiliary information and computing systems to support effective resolution of research tasks.
Dmitrii Shpotya, Nikita Balashov
doaj +1 more source
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Multi-aspect comparative analysis of JavaScript programming frameworks – React.js and Solid.js
Every year, new frameworks and programming libraries appear on the market, trying to gain user interest by presenting their advantages over the competition. The purpose of this article was to compare many aspects of one if such modern solution, i.e. the
Jakub Kryk +1 more
doaj +1 more source
Spreadsheet driven web applications [PDF]
Creating and publishing read-write-compute web applications requires programming skills beyond what most end users possess. But many end users know how to make spreadsheets that act as simple information management applications, some even with computation.
Edward Benson +2 more
openaire +4 more sources
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi +3 more
wiley +1 more source

