Results 41 to 50 of about 2,405,258 (294)

Coixenolide Enhances Antitumor Immunity of Cytotoxic CD8+ T Cells by Inhibiting S100A8/A9‐CD36 Axis in Obesity‐Associated Pancreatic Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen   +20 more
wiley   +1 more source

Promoting Digital Literacy

open access: yesKhizanah al-Hikmah
This study investigates the challenges and strategies associated with implementing web archiving across various institutions in Indonesia, including Universitas Terbuka, Universitas Sumatera Utara, Universitas Mataram, Universitas Diponegoro, Institut ...
Herman Setyawan   +3 more
doaj   +1 more source

RNAi in the Rhizarian Phytopathogen Plasmodiophora brassicae: The Causal Agent of Clubroot Disease in Cruciferous Crops

open access: yesAdvanced Science, EarlyView.
This study uncovers an unusual RNAi pathway in the rhizarian pathogen Plasmodiophora brassicae. In the absence of Dicer, a Drosha‐like RNase III protein supports the biogenesis of predominant 21‐nt small RNAs, and two Argonaute proteins mediate small RNA‐guided silencing.
Xiong Zhang   +13 more
wiley   +1 more source

AvaTar: Zero-Copy Archiving With New Kernel-Level Operations

open access: yesIEEE Access, 2020
The problem associated with current file archiving systems is a slow processing time owing to unnecessary data copying. To address this problem, a novel archiving system with zero-copy merging and splitting operations, referred to as AvaTar, is presented
Hyunchan Park, Youngpil Kim, Seehwan Yoo
doaj   +1 more source

ANXA2+ Small Extracellular Vesicles Drive Chemoresistance in Anaplastic Thyroid Cancer by Promoting XRCC5 Lactylation and Enhancing Non‐Homologous End‐Joining Repair

open access: yesAdvanced Science, EarlyView.
ANXA2+ sEVs promote cisplatin resistance in ATC by stabilizing the SRC/LDHA interaction, increasing LDHA phosphorylation and activity, and lactate production. Elevated lactate levels promote KAT5‐mediated lactylation of XRCC5 at lysine 265, enhancing its binding to XRCC6.
Shanshan Su   +4 more
wiley   +1 more source

A New Approach to Research Data Archiving for WDS Sustainable Data Integration in China

open access: yesData Science Journal, 2013
The World Data System (WDS) requires that WDS data centers have significant data holdings and sustainable data sources integration and sharing mechanism. Research data is one of the important science data resources, but it is difficult to be archived and
Juanle Wang   +4 more
doaj   +1 more source

Current Quality Assurance Practices in Web Archiving [PDF]

open access: yes, 2014
This paper presents the results of a survey of quality assurance (QA) practices within the field of web archiving. To understand current QA practices, the authors surveyed 54 institutions engaged in web archiving, which included national libraries ...
Ko, Lauren   +2 more
core  

Closing the Empirical Loop: Autonomous AI Agents Conduct End‐to‐end Research With Human Participants

open access: yesAdvanced Science, EarlyView.
A multi‐agent AI system autonomously executes the complete scientific workflow, from hypothesis to manuscript, across three psychological studies involving 288 participants. The system designs experiments, collects real world data, develops analysis pipelines, and writes manuscripts with theoretical rigor comparable to experienced researchers.
Gabrielle Wehr   +6 more
wiley   +1 more source

Kako nastajajo spletni arhivi: tehnični vidiki zajemanja spletnih vsebin / How are web archives created? Technical aspects of web content capture [PDF]

open access: yesOrganizacija Znanja
Web archives are collections produced by libraries and other heritage institutions to permanently preserve online heritage. They often contain large amounts of material stored from the web through the use of web crawlers.
Janko Klasinc
doaj  

Web Archiving as a Task of National and Local History Bibliography

open access: yesБиблиосфера, 2021
The foreign experience of forming the majority of national web archives (in national libraries) and many accessible local history archives of public and university libraries has been analyzed due to the development of a model and methodology for ...
N. M. Balatskaya, M. B. Martirosova
doaj   +1 more source

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