Results 41 to 50 of about 659,741 (268)

Maintenance-Ready Web Application Development [PDF]

open access: yesInformatică economică, 2016
The current paper tackles the subject of developing maintenance-ready web applications. Maintenance is presented as a core stage in a web application’s lifecycle.
Ion IVAN   +3 more
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Challenges Related to Approximating the Energy Consumption of a Website

open access: yesIEEE Access
Based on a rough estimate, the ICT industry consumes 7 to 10% of the world’s energy, and around 70% of this is related to usage while the rest can be considered embodied due to manufacturing, logistics, and related activities.
Janne Kalliola, Juho Vepsalainen
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

open access: yesFEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav   +4 more
wiley   +1 more source

PKM Pengembangan Kemampuan Intelektual Guru dan Siswa dalam Web Desain di SMK Negeri 5 Jayapura

open access: yesEthos: Jurnal Penelitian dan Pengabdian kepada Masyarakat, 2020
. Program Kemitraan Masyarakat (PKM) for Developing Intellectual Capabilities of Teachers and Students in Web Design at SMK Negeri 5 Jayapura aims to overcome the problems faced by SMK Negeri 5 Jayapura (partners).
Liza Angriani, Abd. Rachman Dayat
doaj   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

open access: yesAging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi   +3 more
wiley   +1 more source

Effect of Anglocentrism on the Translation of Web Development Documentation into Russian

open access: yesВестник Северного (Арктического) федерального университета: Серия «Гуманитарные и социальные науки»
This study examines the Anglocentric nature of terminology in web development as a factor shaping the perception and translation of technical documentation into Russian.
Viacheslav E. Vovchenko
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Lunor: A Domain-Specific Language with Language Server Protocol Support for Rapid Prototyping of Front-End Web Applications

open access: yesMathematics
Modern web application development using frameworks such as React often requires writing a significant amount of initial code before reaching the stage where development becomes engaging.
Tomaž Kosar   +3 more
doaj   +1 more source

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