Results 71 to 80 of about 3,507,851 (336)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Knowledge web: realising the semantic web... all the way to knowledge-enhanced multimedia documents [PDF]

open access: yes, 2004
The semantic web and semantic web services are major efforts in order to spread and to integrate knowledge technology to the whole web. The Knowledge Web network of excellence aims at supporting their developments at the best and largest European level ...
Euzenat, J.   +3 more
core   +3 more sources

MOOC Cubes and Clouds - Cloud Native Open Data Sciences for Earth Observation [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
The "Cubes and Clouds" Massive Open Online Course (MOOC) addresses the growing challenges and opportunities in Earth Observation (EO) data analysis posed by the exponential growth of satellite missions and data volumes.
P. J. Zellner   +9 more
doaj   +1 more source

Application of Waterfall Model In Development of Work Training Acceptance System

open access: yesIntensif: Jurnal Ilmiah Penelitian Teknologi dan Penerapan Sistem Informasi, 2020
Unemployment became a social problem for the community, so they could not meet their life needs. One cause because they do not have special skills, so it is difficult to get a job. Therefore, in every local government through the UPTD Balai Tenaga Kerja,
Nur Hidayati, Sismadi Sismadi
doaj   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

The Impact of Artificial Intelligence Enhanced No-Code Software Development Platforms on Software Processes: A Literature Review

open access: yesDüzce Üniversitesi Bilim ve Teknoloji Dergisi
This literature review examines the impact of artificial intelligence-based (AI-based) no-code software development platforms on software processes.
Osman Koç   +2 more
doaj   +1 more source

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