Results 111 to 120 of about 2,048,445 (184)

TCMD: A High‐Throughput and Rapid Method for Screening Antimicrobial Ingredients from Renewable Bio‐Based Resources

Advanced Science, EarlyView.
This study develops a strategy to screen the active compounds from bio‐mixtures via combining transcriptomic profiling and molecular docking. The proposed method demonstrates 100% correction in three different biobased mixtures and is 3–20 times faster than traditional approaches.
Yongdong Xu, Yueyao Wang, Yongming Chen, Yunxia Wang, Shicheng Zhang, Gang Luo, Fuhao Cui, Taisheng Du, Zhidan Liu   +8 more
wiley   +1 more source

Genomic Variation Underpins Genetic Divergence and Differing Salt Resilience in Sesbania bispinosa

Advanced Science, EarlyView.
Sesbania, a leguminous halophyte, thrives in saline soils. Comparative genomics reveals key genomic variations—particularly chromosomal inversions—are identified as contributors to population differentiation and salt resilience. These findings advance the understanding of genomic variation driving evolution and phenotypic differentiation and offer ...
Gai Huang, Xiaofei Wang, Chengli Liu, Kaixuan He, Xiu‐Li Hou, Haofei Luo, Shuaibin Zhang, Changqing You, Yajun Jia, Fuqiang Wang, Xianwei Song, Guodao Liu, Xian Deng, Xiaofeng Cao   +13 more
wiley   +1 more source

deepTFBS: Improving within‐ and Cross‐Species Prediction of Transcription Factor Binding Using Deep Multi‐Task and Transfer Learning

Advanced Science, EarlyView.
DeepTFBS leverages deep learning to predict transcription factor binding sites across species, integrating multi‐task and transfer learning approaches to improve performance in data‐scarce scenarios. This study demonstrates enhanced accuracy in intra‐ and cross‐species prediction, revealing conserved regulatory patterns and functional variants.
Jingjing Zhai, Yuzhou Zhang, Chujun Zhang, Xiaotong Yin, Minggui Song, Chenglong Tang, Pengjun Ding, Zenglin Li, Chuang Ma   +8 more
wiley   +1 more source

Light‐Driven PAA Adhesive: A Green Bonding Platform Integrating High‐Performance, Environmental Resilience, and Closed‐Loop Recyclability

Advanced Science, EarlyView.
This investigation introduces the formulation of a cutting‐edge, robust polyacrylic aqueous adhesive (PAA), synthesized through the employment of visible‐light initiated polymerization. The adhesive demonstrates minimal energy demand, environmental friendliness, robust adhesive properties (20.86 MPa on wood), remarkable thermal stability (with ...
Xueying Fu, Jingtian Chen, Yuqi Zhao, Yanan Liu, Chenyang Xie, Xuhang Zhang, Yingdan Liu, Jingyue Yang   +7 more
wiley   +1 more source

Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset

Advanced Science, EarlyView.
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu, Zhengyuan Zhou, Sascha Schäuble, Wolfgang Vivas, Karen Dlubatz, Michael Bauer, Sebastian Weis, Mervyn Singer, Roman Lukaszewski, Gianni Panagiotou   +9 more
wiley   +1 more source

Multiscale Organization of Neural Networks in a 3D Bioprinted Matrix

Advanced Science, EarlyView.
A 3D bioprint model of primary neurons has been engineered with a millimeter‐scale functional neural network, and it recapitulates in vivo transcriptomic features under both normal and disease conditions to the greatest extent. The successful integration of mature neurons and 3D bioprinting signifies a major advance in neuroscience modeling ...
Huiyu Yang, Jiangang Zhang, Yiran Li, Zihan Zhong, Wenhua Li, Haojun Luo, Yanyong Liu, Liujian Ouyang, Zhuoran Jiang, Yuning Sun, Hang Sun, Lulu Liu, Huayu Yang, Yu Wang, Nan Yang, Wenbin Ma, Yilei Mao   +16 more
wiley   +1 more source

Genetic Impacts on the Structure and Mechanics of Cellulose Made by Bacteria

Advanced Science, EarlyView.
A genetic mutation in a protease of a cellulose‐overproducing evolved bacterium significantly affects the proteome, structure, and mechanical properties of bio‐fabricated cellulose pellicles. By overexpressing synthase proteins that build the cellulose‐forming biological machinery of the cell, the evolved bacterium generates dense, stiff, and strong ...
Julie M. Laurent, Mathias Steinacher, Anton Kan, Maximilian Ritter, Mario Leutert, Siiri Bienz, David Häberlin, Naresh Kumar, André R. Studart   +8 more
wiley   +1 more source

Soft and Stretchable Thienopyrroledione‐Based Polymers via Direct Arylation

Advanced Electronic Materials, EarlyView.
π‐conjugated polymers (CPs) that are concurrently soft and stretchable are needed for deformable electronics. This systematic molecular weight study on promising candidates for soft CPs, poly(indacenodithiophene‐co‐thienopyrroledione) (p(IDTC16‐TPDC8)) and poly(indacenodithienothiophene‐co‐thienopyrroledione) (p(IDTTC16‐TPDC8)) found that p(IDTC16 ...
Angela Lin, Lorenzo Guio, Garrett LeCroy, Stanley Lo, Adnan Sharif, Yunfei Wang, Alberto Salleo, Xiaodan Gu, Christine K. Luscombe, Helen Tran   +9 more
wiley   +1 more source

Highly Efficient and Flexible Thin Film Thermoelectric Materials from Blends of PEDOT:PSS and AgSb0.94Cd0.06Te2

Advanced Electronic Materials, EarlyView.
Highly mechanically stable and flexible composite TE thin films based on PEDOT:PSS and AgSb0.94Cd0.06Te2 blend are fabricated. Simultaneous enhancement of S and σ is achieved in the whole blend regime. A very high Seebeck coefficient (204.9 µV K−1) and a power factor of 53.45 µW m−1 K−2 are obtained for 97.5 wt.% AgSb0.94Cd0.06Te2 content.
Mahima Goel, Adrian Hochgesang, Animesh Bhui, Kanishka Biswas, Mukundan Thelakkat   +4 more
wiley   +1 more source

Orbital and Electrical Dual Function of Polymer Intercalant for Promoting NH4+ Storage in Vanadium Oxide Anode

Advanced Energy Materials, Volume 15, Issue 11, March 18, 2025.
The impact of polyaniline insertion on the atomic orbitals and electronic structure of vanadium oxide anode is systematically investigated for the first time. The electrode exhibits an outstanding capacity and unprecedent long‐term cycling life, owing to the electron transition to the V 3dxy state and the enhanced diffusion kinetics.
Yue Zhang, Zihang Huang, Lei Lei, Hua Fan, Xu Han, Hui Li, Tianyi Ma   +6 more
wiley   +1 more source