Results 41 to 50 of about 476,837 (267)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

The organization of knowledge: bibliometric study in database ISI Web of Knowledge

open access: yesBiblios, 2013
The Organization of Knowledge is an area of multiple applications and very traditional in research / teaching in Information Science. Most of the literature deals with the process, activities and tools specially developed for the treatment of documents ...
Cláudia Daniele de Souza
doaj   +1 more source

Bibliometric Analysis of the Permafrost Research: Developments, Impacts, and Trends

open access: yesRemote Sensing, 2022
Permafrost is a significant part of the cryosphere, which has gained increasing attention from scientists, policy-makers, and the general public due to global warming, environmental degradation, water shortages, and intense human activities.
Qingsong Du   +12 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Expanding the Web of Knowledge

open access: yesProceedings of the 30th ACM Conference on Hypertext and Social Media, 2019
Textbooks are educational documents created, structured and formatted in a way that facilitates understanding. Most digital textbooks are released as mere digital copies of their printed counterparts. We present a mechanism that extracts knowledge models from textbooks and enriches their content with additional links (both internal and external).
Isaac Alpizar Chacon   +1 more
openaire   +3 more sources

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Mapping knowledge management research: a bibliometric overview

open access: yesTechnological and Economic Development of Economy, 2021
In recent years, knowledge management (KM) has consistently attained considerably growing research attention. Consequently, several literature reviews have been performed addressing different topic areas of KM. This paper seeks to present a comprehensive
Shashi   +3 more
doaj   +1 more source

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