ABSTRACT Introduction Adolescent siblings of children with cancer are at elevated risk for psychosocial problems. Unfortunately, various barriers such as limited family time and resources, conflicting schedules, and psychosocial staffing constraints at cancer centers hinder sibling access to support.
Christina M. Amaro +10 more
wiley +1 more source
Global and Local Buckling Behavior of Bracing Members with Slotted-in Web Openings
This study examines the global and local buckling behavior of segmented bracing members with slotted-in web openings, designed to reduce the demand on the mid-segment.
Ananda Insan Firdausy, Chong-Jun Lin
doaj +1 more source
Implementing Health‐Related Quality of Life Assessment in Pediatric Oncology: A Feasibility Study
ABSTRACT Background There is growing interest in embedding health‐related quality of life (HRQoL) assessment and patient‐reported outcome measures (PROMs) within clinical cancer care. This study evaluated the feasibility, acceptability, and usability of implementing an electronic PROM (ePROM) platform to measure HRQoL in children with cancer ...
Mikaela Doig +13 more
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
The effectiveness of CFRP strengthening of steel plate girders with web opening subjected to shear
The present study is experimental by nature; it involves applying shear buckling test on seven steel-plated girders that are subjected to shear loading.
Hamood Mohammed +2 more
doaj +1 more source
Structural analysis of a composite continuous girder with a single rectangular web opening
In the design of most bridge girders with composite girders composed of steel–concrete composite plate girders, an opening in the steel girder is often used to provide passage for utility ducts and pipes.
Mohamed A. ElShaer
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
On the Shear Force Redistribution in Composite Steel and Concrete Beams with Web Openings
As far as research into the field of composite steel and concrete beams with web openings has shown, the initiation of a complex stress state due to the introduction of web openings is, unfortunately, inevitable.
Jakub Bartus, Jaroslav Odrobinak
doaj +1 more source
“Discover your own Ireland”: Virtual Ireland(s) for an international audience [PDF]
Copyright @ 2009 University of GlasgowThe opening years of the twenty-first century can be characterised by the increased overlap between cyberspace and the physical world; virtual reality is more real than it has ever been.
Lynch, C
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source

