Results 101 to 110 of about 1,770,021 (263)

Facilities Management and Digital Application of Web Engineering: Implications for Business Informatics Systems

open access: yesKnowledge Management & E-Learning: An International Journal, 2010
A challenge that is facing businesses every day is that of how to promote themselves on the still vastly growing electronic stage. A company‟s web presence connotes a great deal to its customers, including how professional and reliable the organisation ...
Ezendu Ariwa, Marios Michael
doaj  

Using Web Page Titles to Rediscover Lost Web Pages

open access: yes, 2010
49 pages, 18 figures, CS project ...
Shipman, Jeffery L.   +2 more
openaire   +2 more sources

Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome

open access: yesAdvanced Science, EarlyView.
By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang   +12 more
wiley   +1 more source

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

open access: yesAdvanced Science, EarlyView.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu   +15 more
wiley   +1 more source

Enhancing SEO in Single-Page Web Applications in Contrast With Multi-Page Applications

open access: yesIEEE Access
This paper comprehensively reviews methods for improving single-page applications’ visibility (SPAs) and user experience, focusing on the intricacies of search engine optimisation (SEO).
Karolina Kowalczyk, Tomasz Szandala
doaj   +1 more source

Design of an Interface for Page Rank Calculation using Web Link Attributes Information [PDF]

open access: yes
This paper deals with the Web Structure Mining and the different Structure Mining Algorithms like Page Rank, HITS, Trust Rank and Sel-HITS. The functioning of these algorithms are discussed.
Ehtesham HAZARIKA   +2 more
core  

Neutrophil‐Mimetic Nanoscavengers Target the Inflammatory Microenvironment to Eliminate NETs/ROS and Immunomodulate cGAS‐STING Signaling in Septic AKI

open access: yesAdvanced Science, EarlyView.
Sepsis‐associated acute kidney injury is driven by oxidative stress, NETs overproduction, and dysregulated innate immunity. Here, we develop neutrophil‐mimetic nanoscavengers that integrate ROS‐scavenging Mn3O4 nanozymes with DNase‐1‐mediated NETs degradation to suppress cGAS‐STING signaling, reprogram macrophage polarization, and effectively alleviate
Zening Zhang   +9 more
wiley   +1 more source

Promoter Hypermethylation‐Induced Silencing of FXYD1 Drives Breast Cancer Metastasis via DDX5‐Mediated Wnt/β‐Catenin Pathway Activation

open access: yesAdvanced Science, EarlyView.
This study identifies FXYD1 as an epigenetically silenced tumor suppressor in breast cancer. DNA methylation turns off the gene FXYD1 in breast cancer, and low levels predict worse outcomes. Restoring FXYD1 limits breast cancer cells proliferation and metastasis. In the nucleus, FXYD1 recruits the E3 ligase MAEA to K63‐ubiquitinate DDX5 for proteasomal
Ping Wen   +11 more
wiley   +1 more source

SemWeB Semantic Web Browser – Improving Browsing Experience with Semantic and Personalized Information and Hyperlinks

open access: yes, 2009
Imagine a Web browser that can understand the context of a Web page and recommends related semantic hyperlinks in any Web domain. In addition, imagine this browser also understands your browsing needs and personalizes information for you.
De Roure, David   +2 more
core  

CircRSU1 Activates the hnRNPA1/HIF‐1α/CD24 Signaling Axis, Promoting Stemness Features of Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
This study reveals circRSU1 with important oncogenic roles in hepatocellular carcinoma (HCC). CircRSU1, highly abundant in HCC, interacts with and stabilizes hnRNPA1 from ubiquitination and degradation. This stabilization facilitates hnRNPA1 binding to the internal ribosome entry site of HIF1A to increase HIF‐1α protein translation.
Shuting Xue   +14 more
wiley   +1 more source

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