Results 111 to 120 of about 1,770,021 (263)

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

open access: yesAdvanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong   +24 more
wiley   +1 more source

SATB2 Mediates H3K9 Delactylation by Recruiting HDAC3 to Repress LCN2 and Inhibit Lung Tumor Growth and Metastasis

open access: yesAdvanced Science, EarlyView.
This study highlights the capacity for tumor suppressor SATB2 to recruit HDAC3 and catalyze histone H3K9 delactylation, thereby repress transcription of the oncogene LCN2. This novel epigenetic‐metabolic axis inhibits the growth and metastasis of non‐small cell lung cancer, delineating a new mechanistic pathway with potential therapeutic relevance ...
Ting Wen   +10 more
wiley   +1 more source

Programmable Semi‐Interpenetrating Living Materials With Robust Stability for Versatile Bioremediation and Biotherapeutics

open access: yesAdvanced Science, EarlyView.
A semi‐interpenetrating engineered living material (sIHSELM), fabricated via thermosensitive hydroxybutyl chitosan and covalent protein self‐assembly, demonstrates exceptional mechanical properties and environmental stability. Shielding bacteria from harsh conditions, sIHSELM exhibits remarkable efficacy in ulcerative colitis treatment and pollutants ...
Zixian Bao   +8 more
wiley   +1 more source

An Approach to Page Ranking Based on Discourse Structures

open access: yesJournal of Communications Software and Systems, 2016
World Wide Web (WWW) which is predominant source for Information Retrieval today (IR) is essentially a set of hyperlinked documents. A web page containing more number of related hyperlinks satisfy the user needs in a single page.
Subalalitha Chinnaudayar Navaneethakrishnan   +1 more
doaj  

A Novel GmSIN1‐GmRNF1a‐GmCSN5a Module Determines Soybean Salt Tolerance and Yield Under Saline Soil Conditions

open access: yesAdvanced Science, EarlyView.
Soybean production is severely threatened by salt stress. This study reveals that the GmSIN1‐GmRNF1a‐GmCSN5a module enhances salt tolerance by stabilizing the GmSIN1 protein. GmRNF1a acts as an E3 ligase to ubiquitinate GmSIN1 for degradation, a process inhibited by GmCSN5a.
Jinlong Xu   +15 more
wiley   +1 more source

Cell Cycle‐Specific Regulation of Centrosome Clustering Dynamics in Cancer Cells by the Multifunctional Kinesin HSET

open access: yesAdvanced Science, EarlyView.
CDK5RAP2 associates with the kinesin HSET and forms co‐condensates. HSET motors drive the directional transport of CDK5RAP2 condensates toward microtubule minus ends. During mitosis, HSET self‐assembly further stabilizes clustered centrosomes, thereby enabling pseudo‐bipolar spindle formation in cancer cells with supernumerary centrosomes. Upon mitotic
Po‐Pang Chen   +11 more
wiley   +1 more source

Web Page Streams and Relevance Propagation for Topic Distillation

open access: yesInternational Journal of Information and Communication Technology Research, 2014
Over the past decade, several studies in field of relevance propagation models have been proposed to improve quality of web search, which include hyperlink-based score propagation, hyperlinkbased term propagation and popularity-based relevance ...
Mohammad Amin Golshani   +1 more
doaj  

opXRD: Open Experimental Powder X‐Ray Diffraction Database

open access: yesAdvanced Intelligent Discovery, EarlyView.
We introduce the Open Experimental Powder X‐ray Diffraction Database, the largest openly accessible collection of experimental powder diffractograms, comprising over 92,000 patterns collected across diverse material classes and experimental setups. Our ongoing effort aims to guide machine learning research toward fully automated analysis of pXRD data ...
Daniel Hollarek   +23 more
wiley   +1 more source

ResearchConnect: An AI‐Powered Platform for Interdisciplinary Research Team Formation and Ideation Development

open access: yesAdvanced Intelligent Systems, EarlyView.
ResearchConnect is an AI‐powered platform that automates researcher profiling, interdisciplinary team formation, and early‐stage research ideation. By extracting keywords from papers and web sources, it quickly clusters researchers into coherent teams and generates collaborative ideas using large language models. Validation on NSF‐funded projects shows
Akshay Vilas Jadhav   +2 more
wiley   +1 more source

Comparison of Web Page Rendering Methods Based on Next.js Framework Using Page Loading Time Test

open access: yesTeknika
In the rapidly developing digital age, websites have become indispensable for interaction, information dissemination and transaction. To improve the performance of web applications, choosing the right rendering technology is critical.
Roy Hanafi, Abd Haq, Ninik Agustin
doaj   +1 more source

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