Results 61 to 70 of about 2,739,664 (334)

Acod1 Promotes PAD4 Ubiquitination via UBR5 Alkylation to Modulate NETosis and Exert Protective Effects in Sepsis

open access: yesAdvanced Science, EarlyView.
In this study, Acod1 knockout in CLP mice significantly increases peripheral blood NET levels, exacerbating inflammation, organ damage, and reducing survival. Further research shows that UBR5 interacts with PAD4, a key NET formation protein. Acod1/itaconate (ITA) enhances the enzymatic activity of UBR5 by alkylating the Cys2768 site, promoting the K48 ...
Huifan Liu   +10 more
wiley   +1 more source

Dynamically insert the forest plot into a web page: The full Javascript codes [PDF]

open access: yesComputational Ecology and Software
In present study a method that enables users to dynamically insert the forest plot into a web page was presented. In this method, I created a Javascript module for generating and inserting a HTML table, including an entry function and two sub-functions ...
WenJun Zhang
doaj  

Finding pages on the unarchived Web [PDF]

open access: yesIEEE/ACM Joint Conference on Digital Libraries, 2014
Web archives preserve the fast changing Web, yet are highly incomplete due to crawling restrictions, crawling depth and frequency, or restrictive selection policies-most of the Web is unarchived and therefore lost to posterity. In this paper, we propose an approach to recover significant parts of the unarchived Web, by reconstructing descriptions of ...
Huurdeman, H.C.   +4 more
openaire   +3 more sources

Tumor‐Associated Sympathetic Nerves Promote the Progression of Epstein‐Barr Virus‐Positive Diffuse Large B‐Cell Lymphoma

open access: yesAdvanced Science, EarlyView.
Sympathetic nerve innervation promotes the progression of Epstein‐Barr virus‐positive diffuse large B‐cell lymphoma (EBV+ DLBCL) via β2‐adrenergic receptors. The discovery of enhanced nerve infiltration and β2AR expression reveals a novel mechanism and highlights the sympathetic–β2AR axis as a promising target for therapeutic intervention in EBV+ DLBCL.
Silan Huang   +10 more
wiley   +1 more source

Calypso: a user-friendly web-server for mining and visualizing microbiome–environment interactions

open access: yesBioinform., 2016
Calypso is an easy‐to‐use online software suite that allows non‐expert users to mine, interpret and compare taxonomic information from metagenomic or 16S rDNA datasets.
Martha Zakrzewski   +6 more
semanticscholar   +1 more source

Disruption of ARID1B Recruitment to the Nuclear Pore Complex as a New Anticancer Therapeutic Strategy

open access: yesAdvanced Science, EarlyView.
This study identifies ARID1B as a chromatin‐bound driver of tumor growth in TNBC. ARID1B impairs ARID1A function and directly activates oncogenic programs through SWI/SNF remodeling. Its nuclear localization, mediated by the KPNA2–KPNB1–RANBP2 import machinery, is essential for its tumor‐promoting activity.
Olena Odnokoz   +14 more
wiley   +1 more source

AUTOMATIC TAGGING OF PERSIAN WEB PAGES BASED ON N-GRAM LANGUAGE MODELS USING MAPREDUCE [PDF]

open access: yesICTACT Journal on Soft Computing, 2015
Page tagging is one of the most important facilities for increasing the accuracy of information retrieval in the web. Tags are simple pieces of data that usually consist of one or several words, and briefly describe a page.
Saeed Shahrivari   +2 more
doaj  

Trident Web page

open access: yes, 2012
An Extensive Diagnostic Suite Enables Cutting-edge Research at Trident The Trident Laser Facility at Los Alamos National Laboratory is an extremely versatile Nd:glass laser system dedicated to high energy density physics research and fundamental laser-matter interactions.
Juan C. Fernandez, Randall P. Johnson
openaire   +3 more sources

Phosphorylation‐Dependent Stabilization of Collaborator of ARF (CARF) Suppresses Lymphoma Cell Proliferation

open access: yesAdvanced Science, EarlyView.
This study revealed that oncogene Collaborator of ARF (CARF) is closely related to B‐cell lymphoma tumorigenesis, and shares a conserved mechanism regulating protein stability with Arabidopsis Kip‐Related Protein6 (KRP6) through casein kinase 1‐mediated phosphorylation. Reduced phosphorylation led to the enhanced protein stability of CARF, resulting in
Li Qu   +7 more
wiley   +1 more source

Gompertz Law‐Based Biological Age (GOLD BioAge): A Simple and Practical Measurement of Biological Ageing to Capture Morbidity and Mortality Risks

open access: yesAdvanced Science, EarlyView.
The Gompertz law‐based biological age metric (GOLD BioAge) introduces interpretable convenient and interpretable calculations to capture mortality, disease, and frailty risks. Its applications to proteomics and metabolomics (ProtAge and MetAge) demonstrate clinical potential to enhance aging evaluation and prevent age‐related diseases.
Meng Hao   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy