Results 61 to 70 of about 151,568 (281)

Mammalian Proteome Profiling Reveals Readers and Antireaders of Strand‐Symmetric and ‐Asymmetric 5‐Hydroxymethylcytosine‐Modifications in DNA

open access: yesAdvanced Science, EarlyView.
ABSTRACT The cytosine (C) modifications 5‐methylcytosine (mC) and 5‐hydroxymethylcytosine (hmC) are central regulatory elements of mammalian genomes. Both marks occur in double‐stranded DNA in either strand‐symmetric or ‐asymmetric fashion, but it is still poorly understood how this symmetry information is selectively read out by the nuclear proteome ...
Lena Engelhard   +8 more
wiley   +1 more source

Exploring determining factors of web transparency in the world's top universities

open access: yesRevista de Contabilidad: Spanish Accounting Review, 2018
This paper aims to analyze the online transparency of the top 100 Universities in the world and determine which factors influence the degree of online transparency achieved by these institutions.
LAURA SARAITE SARIENE   +2 more
doaj   +3 more sources

Lipid‐Driven OLR1/FOXM1/FGF19 Axis Orchestrates Crosstalk in an Epithelial‐Fibroblast Positive Feedback Promoting Progesterone Resistance in Endometrial Cancer

open access: yesAdvanced Science, EarlyView.
It is revealed that a metabolic–stromal loop driven by oxLDL–OLR1–FOXM1–FGF19 signaling promotes progesterone resistance in endometrial cancer. OxLDL activates epithelial–fibroblast crosstalk, enhancing proliferation and hormonal insensitivity. Disruption of this circuit, especially with resveratrol, restores MPA sensitivity, highlighting a potential ...
Xingchen Li   +9 more
wiley   +1 more source

PAGINA WEB DE INVESTIGACION CUALITATIVA WEB PAGE OF QUALITATIVE INVESTIGATION

open access: yesRevista Habanera de Ciencias Médicas, 2009
Las páginas web son una plataforma de desarrollo de programas. ¹ El número de computadoras conectadas en red ha crecido con rapidez y hoy es el mecanismo de información más grande del mundo.
Leonel Tuya Pendás   +1 more
doaj  

EVALUATION OF WEB SEARCHING METHOD USING A NOVEL WPRR ALGORITHM FOR TWO DIFFERENT CASE STUDIES [PDF]

open access: yesICTACT Journal on Soft Computing, 2012
The World-Wide Web provides every internet citizen with access to an abundance of information, but it becomes increasingly difficult to identify the relevant pieces of information.
V. Lakshmi Praba, T. Vasantha
doaj  

Folic Acid‐Modified Ginger‐Derived Exosome‐Like Nanoparticles Co‐Delivering Sunitinib Suppress Renal Cell Carcinoma via PI3K‐Akt Pathway Inhibition, P‐gp Downregulation, and Macrophage Reprogramming

open access: yesAdvanced Science, EarlyView.
FPD‐GELNs co‐deliver Su and bioactive components. This active‐passive dual‐targeting strategy suppresses the progression of RCC through the following mechanisms: 1) inhibition of the PI3K‐Akt signaling pathway; 2) downregulation of ABCB1/P‐gp to enhance the chemosensitivity of RCC to Su; and 3) reprogramming of macrophages toward M1 polarization and ...
Haoyu Xu   +8 more
wiley   +1 more source

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