Results 61 to 70 of about 2,686,138 (315)

Single‐Nucleus Multi‐Omics Reveals Hypoxia‐Driven Angiogenic Programs and Their Epigenetic Control in Sinonasal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You   +12 more
wiley   +1 more source

545 Incorporating user feedback to enhance OpenRegSource – A researcher’s portal to regulatory information

open access: yesJournal of Clinical and Translational Science
Objectives/Goals: This study aims to gather user feedback from clinical research professionals on the usefulness and relevance of regulatory resources found on a new regulatory web portal, OpenRegSource, to enhance its usability, thereby advancing this ...
Karen Manrique, Eunjoo Pacifici
doaj   +1 more source

THE WEBPORTAL OF V.O. SUKHOMLYNSKY STATE SCIENTIFIC AND PEDAGOGICAL LIBRARY OF UKRAINE AS AN INFORMATION RESOURCE FOR IMPLEMENTATION OF RESEARCH IN EDUCATION, PEDAGOGY AND PSYCHOLOGY

open access: yesІнформаційні технології і засоби навчання, 2020
In the context of the digital transformation of society and the integration of Ukrainian science and education into the European scientific and educational space, it becomes necessary to carry out high-quality, competitive scientific research which is ...
Larysa D. Berezivska   +2 more
doaj   +1 more source

An Infrastructure for acquiring high quality semantic metadata [PDF]

open access: yes, 2006
Because metadata that underlies semantic web applications is gathered from distributed and heterogeneous data sources, it is important to ensure its quality (i.e., reduce duplicates, spelling errors, ambiguities).
B. Popov   +8 more
core   +4 more sources

HiST: Histological Images Reconstruct Tumor Spatial Transcriptomics via MultiScale Fusion Deep Learning

open access: yesAdvanced Science, EarlyView.
HiST, a multiscale deep learning framework, reconstructs spatially resolved gene expression profiles directly from histological images. It accurately identifies tumor regions, captures intratumoral heterogeneity, and predicts patient prognosis and immunotherapy response.
Wei Li   +8 more
wiley   +1 more source

Patients' Experiences with and Attitudes towards a Diabetes Patient Web Portal. [PDF]

open access: yesPLoS ONE, 2015
A diabetes patient web portal allows patients to access their personal health record and may improve diabetes outcomes; however, patients' adoption is slow. We aimed to get insight into patients' experiences with a web portal to understand how the portal
Maaike C M Ronda   +2 more
doaj   +1 more source

Listening to the patients: using participatory design in the development of a cardiac telerehabilitation web portal.

open access: yesmHealth, 2019
Background Cardiovascular disease is the leading cause of all deaths worldwide. Cardiac rehabilitation is an effective approach for preventing secondary complications, but it remains a complex intervention because of the need for lifestyle changes.
K. Joensson   +6 more
semanticscholar   +1 more source

His‐MMDM: Multi‐Domain and Multi‐Omics Translation of Histopathological Images with Diffusion Models

open access: yesAdvanced Science, EarlyView.
His‐MMDM is a diffusion model‐based framework for scalable multi‐domain and multi‐omics translation of histopathological images, enabling tasks from virtual staining, cross‐tumor knowledge transfer, and omics‐guided image editing. ABSTRACT Generative AI (GenAI) has advanced computational pathology through various image translation models.
Zhongxiao Li   +13 more
wiley   +1 more source

A web portal to promote a sustainable agriculture, preserving biodiversity in the Indian Ocean [PDF]

open access: yes, 2011
The islands of the Indian Ocean are home to a unique and remarkable biodiversity. They have similar environmental conditions and are subject to common threats (e.g. global changes).
Baptiste, Micheline Marie   +3 more
core  

Selenoprotein H Functions as a PPARα Coactivator to Link Selenium Homeostasis to Hepatic Lipid Metabolism and Protect against Steatohepatitis

open access: yesAdvanced Science, EarlyView.
Our study identifies selenium deficiency as a hallmark of MASH pathogenesis. Dietary selenium supplementation enhances hepatic fatty acid oxidation (FAO) and attenuates MASH progression by activating the PPARα pathway via selenoprotein H (SELENOH). This selenium‐SELENOH‐PPARα nexus redefines the functional scope of selenoproteins, moving from redox ...
Yuwei Zhang   +11 more
wiley   +1 more source

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