Results 111 to 120 of about 184,073 (301)

Cell fishing: A similarity based approach and machine learning strategy for multiple cell lines-compound sensitivity prediction.

PLoS ONE, 2019
The prediction of cell-lines sensitivity to a given set of compounds is a very important factor in the optimization of in-vitro assays. To date, the most common prediction strategies are based upon machine learning or other quantitative structure ...
E Tejera, I Carrera, Karina Jimenes-Vargas, V Armijos-Jaramillo, A Sánchez-Rodríguez, M Cruz-Monteagudo, Y Perez-Castillo   +6 more
doaj   +1 more source

Novel Functional Materials via 3D Printing by Vat Photopolymerization

Advanced Functional Materials, EarlyView.
This Perspective systematically analyzes strategies for incorporating functionalities into 3D‐printed materials via Vat Photopolymerization (VP). It explores the spectrum of achievable functionalities in recently reported novel materials—such as conductive, energy‐storing, biodegradable, stimuli‐responsive, self‐healing, shape‐memory, biomaterials, and
Sergey S. Nechausov, Patrick Fesser, Boris A. Bulgakov, Ulrich S. Schubert   +3 more
wiley   +1 more source

HmtDB, a Human Mitochondrial Genomic Resource Based on Variability Studies Supporting Population Genetics and Biomedical Research

BMC Bioinformatics, 2005
Background Population genetics studies based on the analysis of mtDNA and mitochondrial disease studies have produced a huge quantity of sequence data and related information.
Pappadà Graziano, Scioscia Gaetano, Lascaro Daniela, Santamaria Monica, Accetturo Matteo, Attimonelli Marcella, Russo Luigi, Zanchetta Luigi, Tommaseo-Ponzetta Mila   +8 more
doaj   +1 more source

Directory knowledge, query stream and weighted state space tree based automatic web query classification [PDF]

, 2012
S. Lovelyn Rose, L. R. Karlmarx
openalex   +1 more source

Same query - different results? A study of repeat queries in search sessions [PDF]

, 2011
Typically, three main query reformulation types in sessions are considered: generalization, specication, and drift. We show that given the full context of user interactions, repeat queries represent an important reformulation type which should also be ...
Jones, Gareth J.F., Leveling, Johannes
core   +1 more source

Amyloidogenic Peptide Fragments Designed From Bacterial Collagen‐like Proteins Form Hydrogel

Advanced Functional Materials, EarlyView.
This study identified amyloidogenic sequence motifs in bacterial collagen‐like proteins and exploited these to design peptides that self‐assemble into β‐sheet fibers and form hydrogels. One hydrogel supported healthy fibroblast growth, showing promise for biocompatible materials. Our work demonstrates that bacterial sequences can be harnessed to create
Vamika Sagar, Xuen J Ng, Lukas Lechel, Ashish Chand Rajwar, Hendrik Bargel, Abhishek A. Jalan   +5 more
wiley   +1 more source

PURE: A webserver for the prediction of domains in unassigned regions in proteins

BMC Bioinformatics, 2008
Background Protein domains are the structural and functional units of proteins. The ability to parse proteins into different domains is important for effective classification, understanding of protein structure, function, and evolution and is hence ...
Offmann Bernard O, Shameer Khader, Reddy Chilamakuri CS, Sowdhamini Ramanathan   +3 more
doaj   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies

Advanced Healthcare Materials, EarlyView.
Four extracellular vesicle purification strategies are compared using ovarian‐cancer ascites and ES‐2 cell supernatants. A novel workflow links purification to function by combining particle‐normalized proteomics with matched cell‐free and cell‐based assays.
Christian Preußer, Dolores J. Salander, Witold Szymanski, Johannes Graumann, Yukai Wang, Kai Zhao, Jörg W. Bartsch, María Gómez‐Serrano, Daniel Bachurski, Silke Reinartz, Elke von Pogge von Strandmann   +10 more
wiley   +1 more source

An Investigation of Term Weighting and Feature Selection Methods for Sentiment Analysis

Majlesi Journal of Electrical Engineering
Sentiment analysis automatically classifies the opinions, which are expressed in a document, usually as positive or negative. A review document in general, reflects its author’s opinion about the objects mentioned in the text.
Tuba Parlar, Selma Ayşe Özel
doaj