Results 151 to 160 of about 532,216 (314)

Information Searching Tactics of Web Searchers [PDF]

, 2006
This paper examines patterns and features of query reformulation within a Web searching session. We pursued this study in response to the growing interest in the area of interactions during information searching.
Zhang, Mimi, Jansen, Bernard J., Jansen, Bernard, Spink, Amanda   +3 more
core  

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

Advanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng, Yanlin Guo, Liumi Jiang, Jing Luo, Yan Liu, Ziwei Yuan, Pingyang Ke, Ran Duan, Fei Xiao   +8 more
wiley   +1 more source

Tropomyosin 1 Promotes Platelet Adhesion and Clot Contraction Separate from Its Roles in Developmental Hematopoiesis

Advanced Science, EarlyView.
ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung, Victor Tsao, Alina D Peshkova, Oscar A. Marcos‐Contreras, Kim Ha, Brian M Dulmovits, Nkemdilim Okoli, Anvi Sinha, Gennadiy Fonar, Rong Qiu, Rolf D Bates, Janelle Yeboah, Carson Shalaby, Tyler Truex, Soomin Jeong, Edna C Hardeman, Peter W Gunning, Vladimir R Muzykantov, Jacob W Myerson, Christopher S Thom   +19 more
wiley   +1 more source

You are how (and where) you search? Comparative analysis of web search behavior using web tracking data. [PDF]

J Comput Soc Sci, 2023
Urman A, Makhortykh M.
europepmc   +1 more source

CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation

Advanced Science, EarlyView.
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu, Cheng Kiu Ho, Jitao Liu, Lei Cui, Yangfeng Hou, Cai Liang, Wenchu Ye, Randolph H. L. Wong, Shohei Hori, Bin Zhou, Kathy O. Lui   +10 more
wiley   +1 more source

Eczema-related Web Search Data in Sweden: Investigating Search Patterns and the Influence of Weather. [PDF]

Acta Derm Venereol, 2022
Tizek L, Wecker H, Schneider S, Johansson EK, Girmay Y, Zink A.   +5 more
europepmc   +1 more source

Using semantic indexing to improve searching performance in web archives [PDF]

, 2013
The sheer volume of electronic documents being published on the Web can be overwhelming for users if the searching aspect is not properly addressed. This problem is particularly acute inside archives and repositories containing large collections of web ...
Tiropanis, Thanassis, Khan, Arshad, Martin, David, Martin, David J.   +3 more
core  

Tumor‐Derived Alpha‐1 Antitrypsin Promotes Liver Metastasis of Colorectal Cancer Through the Neutrophil Extracellular Traps–CCDC25 Pathway

Advanced Science, EarlyView.
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei, Chunning Li, Lei Zhan, Xiaoyan Li, Yan Hui, Yue Jin, Jing Zhang, Lu Yang, Xin Sun, Xiaoxi Li, Qian Dong, Jingdong Zhang   +11 more
wiley   +1 more source

The Attentive Cursor Dataset

Frontiers in Human Neuroscience, 2020
Luis A. Leiva, Ioannis Arapakis
doaj   +1 more source

Detecting Elevated Air Pollution Levels by Monitoring Web Search Queries: Algorithm Development and Validation. [PDF]

JMIR Form Res, 2022
Lin C, Yousefi S, Kahoro E, Karisani P, Liang D, Sarnat J, Agichtein E.   +6 more
europepmc   +1 more source