Results 251 to 260 of about 2,006,269 (325)

A Tolerance Rough Set Approach to Clustering Web Search Results

, 2004
Chi Lang Ngo, Hung Son Nguyen
openalex   +1 more source

SCORCH2: A Generalized Heterogeneous Consensus Model for High‐Enrichment Interaction‐Based Virtual Screening

Advanced Science, EarlyView.
Researchers developed SCORCH2, an advanced machine‐learning scoring function for virtual screening that combines two complementary XGBoost models to re‐evaluate protein‐ligand binding plausibility. The method demonstrates superior performance on standard benchmarks, shows excellent generalization to previously unseen protein targets, and provides ...
Lin Chen, Vincent Blay, Pedro J. Ballester, Douglas R. Houston   +3 more
wiley   +1 more source

Creating an Empirical Dermatology Dataset Through Crowdsourcing With Web Search Advertisements.

JAMA Netw Open
Ward A, Li J, Wang J, Lakshminarasimhan S, Carrick A, Campana B, Hartford J, Sreenivasaiah PK, Tiyasirisokchai T, Virmani S, Wong R, Matias Y, Corrado GS, Webster DR, Smith MA, Siegel D, Lin S, Ko J, Karthikesalingam A, Semturs C, Rao P.   +20 more
europepmc   +1 more source

Enhancer Reprogramming Reveals the Tumorigenic Role of PTPRZ1 in Lung Squamous Cell Carcinoma

Advanced Science, EarlyView.
Lung squamous cell cancer (LUSC) is deadly due to lack of good treatments. Here, multiomics techniques are applied to LUSC tumors and find thousands of cancer‐specific enhancers controlling key genes. Interestingly, the gene PTPRZ1 is identified as a critical oncogene driven by the LUSC‐acquired enhancers. PTPRZ1 is activated by MDK, fueling cancer via
Yong‐Qiang Ning, Jie Wang, Yihui Zhang, Hongrui Li, Zenan Jiang, Xinyu Su, Xiao Yang, Xiaoxuan Wu, Bing Wei, Jianmin Ying, Jian Yan, Wenbin Li   +11 more
wiley   +1 more source

Leveraging web search data in Germany to identify unmet needs of contraceptives on a population-based level: A longitudinal retrospective study. [PDF]

Womens Health (Lond)
Steiner C, Wecker H, Tizek L, Ziehfreund S, Preis S, Pfister K, Oberländer V, Biedermann T, Zink A.   +8 more
europepmc   +1 more source

Measuring the affective information environment of web searchers

, 2004
Diane Nahl
openalex   +1 more source

Optimal Chirality Enhances Long‐Range Fluctuation‐Induced Interactions in Active Fluids

Advanced Science, EarlyView.
Chiral active particles move along curved trajectories arising from the interplay of propulsion and self‐rotation. How chirality influences fluctuation‐induced forces in active matter systems remains unclear. It is shown that particle shape dictates this effect: chirality suppresses forces for circular particles but can enhance them for elongated ones,
Hashem Fatemi, Hamidreza Khalilian, Jalal Sarabadani, Reza Shaebani   +3 more
wiley   +1 more source

RiboMicrobe: An Integrated Translatome Atlas for Microorganism

Advanced Science, EarlyView.
RiboMicrobe is a comprehensive database for Ribo‐seq data from prokaryotes, featuring 891 Ribo‐seq, 369 RNA‐seq, and 62 proteome datasets from 38 species. The database not only provides various data visualization results but also includes two sORF prediction models and a suit of bioinformatics tools for comparative analysis, facilitating easy access ...
Yingshun Zhou, Jinjing Luo, Xiaoqiang Lang, Yuli Gan, Guoxian Liu, Yuling Cui, Fazhi Li, Weicong Zhu, Bing Chen, Yuanyuan Dong, Yinglin Wu, Yi Cao, Qi Liu   +12 more
wiley   +1 more source

Targeting Mast Cell Activation and MIF‐Mediated Remodelling Enhances Chemotherapy Response in Pancreatic Cancer

Advanced Science, EarlyView.
Neoadjuvant gemcitabine plus nab‐paclitaxel (AG) reprograms pancreatic ductal adenocarcinoma by shifting malignant cells toward a classical phenotype and remodeling the tumor microenvironment. Despite enhancing cytotoxic NKT cells, AG activates tumor‐associated mast cells (TAMCs) and inflammatory CAFs through MIF signaling.
Libo Wang, Guangcong Shen, Guanpeng Xie, Zekun Li, Xiaoqing Ma, Mengyu Li, Ziyun Liu, Yadi Wang, Zongjing Lv, Qingxiao Fang, Huihui Sun, Ningning Zhao, Chao Yang, Tianxing Zhou, Yongjie Xie, Jun Yu, Jihui Hao   +16 more
wiley   +1 more source

Large-Scale Estimation and Analysis of Web Users' Mood from Web Search Query and Mobile Sensor Data. [PDF]

Big Data
Sasaki W, Hamanaka S, Miyahara S, Tsubouchi K, Nakazawa J, Okoshi T.   +5 more
europepmc   +1 more source