Results 171 to 180 of about 341,640 (282)

Re‐Entrant Super‐Repellent Metallic Structures for Robust Anti‐Icing

open access: yesAdvanced Science, EarlyView.
Breakthrough re‐entrant super‐repellent structures engineered on metals demonstrate unprecedented anti‐icing performances: >600 min icing delay, 1.6 kPa ultralow ice adhesion strength, and 100‐cycle deicing durability. Thermodynamic analysis elucidates novel anti‐icing mechanisms and underlying design principles for exceptional ice‐resistance under ...
Daizhou Li   +8 more
wiley   +1 more source

SCORCH2: A Generalized Heterogeneous Consensus Model for High‐Enrichment Interaction‐Based Virtual Screening

open access: yesAdvanced Science, EarlyView.
Researchers developed SCORCH2, an advanced machine‐learning scoring function for virtual screening that combines two complementary XGBoost models to re‐evaluate protein‐ligand binding plausibility. The method demonstrates superior performance on standard benchmarks, shows excellent generalization to previously unseen protein targets, and provides ...
Lin Chen   +3 more
wiley   +1 more source

Hsa_circ_0026782 Acts as a “Molecular Break” of CREB1‐Mediated Transcription by Promoting Its Phosphorylation at Ser142 That Prevents Keloid Progression

open access: yesAdvanced Science, EarlyView.
Model for the role of hsa_circ_0026782/p‐CREB1 (Ser142) played in keloid. Hsa_circ_0026782 is derived from back‐splicing of ITGA7 exon 4. When hsa_circ_0026782 binds to CREB1, the exposure of the bZIP domain and dimerization of CREB1 are promoted (upper left).
Xin‐Cao Zhong   +10 more
wiley   +1 more source

Comparative Single‐Cell Transcriptomic Landscape Reveals the Regulatory Mechanisms of Lactation during Selective Breeding in Asian Water Buffalo

open access: yesAdvanced Science, EarlyView.
In this study, a comprehensive single‐cell transcriptome atlas of river and swamp buffalo, encompassing 12 tissues and 397,011 cells, is constructed. Differential expression analyses identify metabolic and secretory tissues and cell types that mediate the divergence of milk production.
Dongmei Dai   +13 more
wiley   +1 more source

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