Results 171 to 180 of about 521,782 (354)

Image Fusion for Super‐Resolution Mass Spectrometry Imaging of Plant Tissue

open access: yesAdvanced Science, EarlyView.
A loss controlled residual network (LCRN) workflow is developed for super‐resolution fusion of plant mass spectrometry imaging data. LCRN uses a novel edge perceptual loss metric to preserve complex plant tissue morphology. LCRN achieves up to 20‐fold magnification while effectively combining chemical information from mass spectrometry with ...
Yuchen Zou   +3 more
wiley   +1 more source

Energy-price-driven query processing in multi-center web search engines

open access: yesAnnual International ACM SIGIR Conference on Research and Development in Information Retrieval, 2011
Enver Kayaaslan   +4 more
semanticscholar   +1 more source

Genetically‐Programmed Hypervesiculation of Lactiplantibacillus Plantarum Increases Production of Bacterial Extracellular Vesicles with Therapeutic Efficacy in a Preclinical Inflammatory Bowel Disease Model

open access: yesAdvanced Science, EarlyView.
The development of a novel engineered strain of Lactiplantibacillus plantarum (Lp) is reported that can produce bacterial extracellular vesicles (BEVs) at >60‐fold higher yields than the unmodified parental strain. These Lp BEVs retain therapeutic bioactivity as validated in a mouse model of dextran sodium sulfate‐induced colitis.
Nicholas H Pirolli   +16 more
wiley   +1 more source

Targeting the Notch1‐YY1‐ICAM1 Signaling Axis Enhances the Efficacy of Immunotherapy in HCC by Activating CD8+ T‐Cell‐Driven Cancer Cell Pyroptosis

open access: yesAdvanced Science, EarlyView.
In hepatocellular carcinoma (HCC), aberrantly activated Notch1 signaling induces its target gene YY1, which impairs immunotherapy efficacy by suppressing tumor cell‐ICAM1‐driven T cell activation and the mediated pyroptosis of T cells against tumor cells.
Ke Zhu   +10 more
wiley   +1 more source

Functional, Pharmacogenomic, and Immune Landscapes of Long Non‐Coding RNAs in Cancer

open access: yesAdvanced Science, EarlyView.
A systematic analysis of 33 cancer types reveals widespread associations between lncRNAs and cancer pathways, drug responses, immune features, and immunotherapy outcomes. The study identifies key lncRNAs linked to therapeutic response and adverse events and introduces PILNC, an interactive web portal for exploring the functional, pharmacogenomic, and ...
Runhao Wang   +15 more
wiley   +1 more source

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