Results 111 to 120 of about 274,007 (336)

An Allele of Glutamate Formiminotransferase Triggers 5‐Methyl‐Tetrahydrofolate‐to‐MeFox Conversion and Facilitates Folate Biofortification in Maize

open access: yesAdvanced Science, EarlyView.
This work demonstrates the distinct roles of the glutamate formiminotransferase (GFT) enzyme in plants. The GFT triggers the conversion of 5‐methyl‐tetrahydrofolate to MeFox in plants, a process distinct from its role as a formiminotransferase in mammals.
Tong Lian   +15 more
wiley   +1 more source

Disruption of ARID1B Recruitment to the Nuclear Pore Complex as a New Anticancer Therapeutic Strategy

open access: yesAdvanced Science, EarlyView.
This study identifies ARID1B as a chromatin‐bound driver of tumor growth in TNBC. ARID1B impairs ARID1A function and directly activates oncogenic programs through SWI/SNF remodeling. Its nuclear localization, mediated by the KPNA2–KPNB1–RANBP2 import machinery, is essential for its tumor‐promoting activity.
Olena Odnokoz   +14 more
wiley   +1 more source

A Methodology for Simulated Experiments in Interactive Search [PDF]

open access: yes, 2009
Interactive information retrieval has received much attention in recent years, e.g. [7]. Furthermore, increased activity in developing interactive features in search systems used across existing popular Web search engines suggests that interactive ...
Albakour, M   +7 more
core  

RAB5A Promotes Active Fluid Wetting by Reprogramming Breast Cancer Spheroid Mechanics

open access: yesAdvanced Science, EarlyView.
RAB5A‐mediated unjamming enhances active wetting through distinct biomechanical processes: a) upregulation of specific integrin subunits, enhanced focal adhesions kinetics and activity; b) supracellular organization relying on nanoscale integrin clustering, and the formation of a stiff and collective actin cable; and c) softening of the spheroid core ...
Grégoire Lemahieu   +19 more
wiley   +1 more source

Dynamic Neural Deactivation Bridges Direct and Competitive Inhibition Processes

open access: yesAdvanced Science, EarlyView.
Dynamic neural deactivation bridges traditionally distinct inhibitory mechanisms—direct inhibition and competition‐induced inhibition—revealing a common neural signature across modalities. Multimodal neuroimaging and behavioral experiments demonstrate a temporal dynamic characterized by progressive frontoparietal activation decay and enhanced sensory ...
Zhenhong He   +6 more
wiley   +1 more source

Searching heterogeneous collections on the Web: behaviour of Excite users

open access: yesInformation Research: An International Electronic Journal, 1998
As Web search services become a major source of information for a growing number of people, we need to know more about how users search heterogeneous collections using Web search engines. This paper reports the results from a major study exploring users'
Amanda Spink   +2 more
doaj  

A Quantum Query Expansion Approach for Session Search

open access: yesEntropy, 2016
Recently, Quantum Theory (QT) has been employed to advance the theory of Information Retrieval (IR). Various analogies between QT and IR have been established.
Peng Zhang   +6 more
doaj   +1 more source

Knowledge Engineering in Search Engines [PDF]

open access: yes, 2012
With large amounts of information being exchanged on the Internet, search engines have become the most popular tools for helping users to search and filter this information.
Lin, Yun-Chieh
core   +1 more source

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