Results 141 to 150 of about 607,451 (374)

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

open access: yesAdvanced Science, EarlyView.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan   +20 more
wiley   +1 more source

Effective and Efficient Query-aware Snippet Extraction for Web Search [PDF]

open access: green, 2022
Jingwei Yi   +6 more
openalex   +1 more source

Time‐Efficient and Informatic‐Skill‐Light Gap‐Filling for Telomere‐to‐Telomere Genome Assembly

open access: yesAdvanced Science, EarlyView.
The paper introduces a novel auxiliary software toolbox GapSuite, consisting of two tools Gap‐Aid and Gap‐Graph, which guides users to fill gaps in chromosome‐level genome assembly using sequence‐extension‐based and assembly‐graph‐based strategies. The two tools enable users with limited informatics expertise to efficiently complete gap‐filling on ...
Dong Xu   +8 more
wiley   +1 more source

Query Chains: Learning to Rank from Implicit Feedback

open access: yes, 2005
This paper presents a novel approach for using clickthrough data to learn ranked retrieval functions for web search results. We observe that users searching the web often perform a sequence, or chain, of queries with a similar information need.
Joachims, Thorsten, Radlinski, Filip
core   +3 more sources

Experimental Joint Estimation of Phase and Phase Diffusion Via Deterministic Bell Measurements

open access: yesAdvanced Science, EarlyView.
This work employs Bell measurement, a form of entangling measurement, to estimate both the phase and its fluctuations in an optical interferometer. By incorporating a novel quantum effect at the measurement stage, the proposed method achieves the ultimate precision limit and demonstrates the significant potential of entangling measurements in multi ...
Ben Wang   +4 more
wiley   +1 more source

Generating Dynamic Structures Through Physics‐Based Sampling of Predicted Inter‐Residue Geometries

open access: yesAdvanced Science, EarlyView.
While static structure prediction has been revolutionized, modeling protein dynamics remains elusive. trRosettaX2‐Dynamics is presented to address this challenge. This framework leverages a Transformer‐based network to predict inter‐residue geometric constraints, guiding conformation generation via physics‐based iterative sampling. The resulting method
Chenxiao Xiang   +3 more
wiley   +1 more source

The Role of the User's Browsing and Query History for Improving MPC-generated Query Suggestions

open access: yesJournal of Communications Software and Systems, 2019
In this paper we use the user's recent web browsing history in order to provide better query suggestions in an information retrieval system. We have built a Chrome browser plugin that collects each web page visited by a user and submits it to our query ...
Ioan Badarinza   +2 more
doaj  

End-to-end vertical web search pseudo relevance feedback queries recommendation software

open access: yesSoftwareX
Users' web information needs are increasingly exploratory, seeking to navigate unfamiliar domains and discover knowledge. However, existing search engines struggle with ambiguous queries, leading to irrelevant results.
Tajmir Khan   +4 more
doaj   +1 more source

Xanthatin Targets CISD1 to Drive Ferroptosis and Mitophagy as a Dual Anticancer Strategy in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
Triple‐negative breast cancer has a poor prognosis. Xanthatin directly targets and degrades CISD1, triggering ferroptosis through iron dysregulation. The concurrently activated mitophagy synergistically amplifies ferroptotic cell death. Xanthatin also demonstrates potent in vivo anti‐tumor efficacy with minimal toxicity, highlighting its therapeutic ...
Qinwen Liu   +9 more
wiley   +1 more source

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