Results 41 to 50 of about 5,082,258 (258)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Web-site in the universities of physical specialization as instrument of the informational providing of specialists of industry of physical culture and sport [PDF]

Pedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2010
Directions of the informative providing of preparation of specialists are presented on a physical culture and sport. The analysis of informative electronic sources of five educational establishments is presented.
Svistelnyk I.R.
doaj  

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Request for confirmation sequences in Castilian Spanish

Open Linguistics
This article analyzes request for confirmation (RfC) sequences in spoken Castilian Spanish. RfCs are conversational turns that present a proposition for which the speaker claims some knowledge but at the same time asks for an informed co-participant’s ...
Ehmer Oliver
doaj   +1 more source

The Current Online Face of U.S. Academic Ophthalmology

Journal of Academic Ophthalmology, 2018
Purpose To evaluate the comprehensiveness and navigation ease of online content from Web sites of U.S. academic ophthalmology departments. Design Cross-sectional analysis of 117 U.S. academic ophthalmology department Web sites from October 1
Tedi Begaj, Omar Helmy, Samuel Leeman, Shlomit Schaal   +3 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Association between academic stress and caffeine expectancy among medical students in Jeddah Saudi Arabia

Discover Mental Health
Background Medical students experience high stress, often leading to increased caffeine consumption as a coping mechanism. The relationship between specific stressors and caffeine expectancy—beliefs about caffeine’s effects—is poorly understood in the ...
Ayat El-Zayat, Sadia Sultan, Renad Sarhan, Rouz Banjar, Ruba Qadi, Layan Kutub, Rahaf Al-Tuwairqi, Web Site   +7 more
doaj   +1 more source

ICT and cooperative work

Agricultural Economics (AGRICECON), 2005
This article deals with the possibilities of making usage of ICT (Information and communication technology) to support cooperation among teams. There are two main approaches: systems based on the www technologies (intranets), and specialised systems ...
Z. Havlíček, J. Vaněk
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source