Results 231 to 240 of about 1,705,810 (275)

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu, Shizhen Qiu, Zhitong Wang, Dan Li, Min Chen, Yinying Chu, Guangfei Li, Yi Fang, Changjiang Li, Fang Shi, Peijie He, Haitao Wu, Haopeng Wang, Jian Chen   +13 more
wiley   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Tumor‐Derived Alpha‐1 Antitrypsin Promotes Liver Metastasis of Colorectal Cancer Through the Neutrophil Extracellular Traps–CCDC25 Pathway

Advanced Science, EarlyView.
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei, Chunning Li, Lei Zhan, Xiaoyan Li, Yan Hui, Yue Jin, Jing Zhang, Lu Yang, Xin Sun, Xiaoxi Li, Qian Dong, Jingdong Zhang   +11 more
wiley   +1 more source

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Web Sites Related to Methods for Evaluating Web Sites

Physical & Occupational Therapy In Pediatrics, 2002
Caught in the Web is a regular column for regular feature that reviews web sites related to topics of interest and applicability in clinical practice, education, and research. Any comments concerning the topics reviewed or suggestions for future topics are welcome.
K, Janson, M, Law
openaire   +2 more sources

Web-site review

Collegian, 1997
This regular feature will identify and describe interesting and informative sites on the World Wide Web, sites that are relevant to nursing and can help you, the nurse, professionally. It is intended to provide information about sites, evaluate their usefulness for nurses and, hopefully, help reduce search time for Web users.
openaire   +2 more sources

Web sites

Aircraft Engineering and Aerospace Technology, 2001
  +6 more sources

Evaluating Web sites

Nursing, 2003
Carol O, Long, Edward A, Greenberg
openaire   +2 more sources

Web sites

Anti-Corrosion Methods and Materials, 2000
Andruid Kerne, Andy Deck, Claire Dinsmore, David Crawford, Lisa Tilder, Melanitis Yiannis, Diane Ludin   +6 more
  +4 more sources

Trauma web sites

International Journal of Trauma Nursing, 1997
openaire   +2 more sources