Results 31 to 40 of about 64,624 (251)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Evidence for the existence of geographic trends in university web site interlinking [PDF]
, 2002 Main articleThis is an accepted manuscript of an article published by MCB UP Ltd in Journal of Documentation on 01/10/2002, available online: https://doi.org/10.1108/00220410210441586 The accepted version of the publication may differ from the final ...
Thelwall, Mike
core +1 more source
Ciência e Agrotecnologia, 2005 Com este trabalho avaliou-se o que está sendo oferecido pelas empresas operadoras de rastreabilidade credenciadas pelo Ministério da Agricultura, Pecuária e Abastecimento.
Francisco Juraci Rolim +1 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Web Analytics: Web sites, strategies, models, frameworks, software tools & decision support
, 2021 This keynote deals with Web analytics, and will cover associated Web sites, strategies, models, frameworks, software tools & decision support. The speech consists of the following key elements The Web sites & social media platforms. 1.
Li, Shuliang
core
A research and institutional size-based model for national university Web site interlinking [PDF]
, 2002 Web links are a phenomenon of interest to bibliometricians by analogy with citations, and to others because of their use in Web navigation and search engines.
Mike Thelwall, Thelwall, Mike
core +1 more source
TOURISTIC WEB SITES PERFORMANCES AND GOVERNANCE TYPOLOGIES
Enlightening Tourism: A Pathmaking Journal, 2013 The paper aims to highlight and discuss the results of the research, still in progress, about the influence of web sites governance for the touristic promotion of the territory on the criteria through which these communication channels are planned and ...
Massimo Bianchi, Laura Tampieri
doaj +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source