Results 51 to 60 of about 8,127,621 (365)

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Challenges and potential of the Semantic Web for tourism [PDF]

open access: yes, 2012
The paper explores tourism challenges and potential of the Semantic Web from a theoretical and industry perspective. It first examines tourism business networks and explores a main theme of network interoperability - data standards- followed by ...
Buhalis, Dimitrios, Mistilis, N
core  

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

Factors explaining adoption and implementation processes for web accessibility standards within eGovernment systems and organizations

open access: yesUniversal Access in the Information Society, 2015
Local government organizations such as municipalities often seem unable to fully adopt or implement web accessibility standards even if they are actively pursuing it.
E. Velleman, I. Nahuis, T. Geest
semanticscholar   +1 more source

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

open access: yesFEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki   +11 more
wiley   +1 more source

Implementation of clinical research trials using web-based and mobile devices: challenges and solutions

open access: yesBMC Medical Research Methodology, 2017
Background With the increasing implementation of web-based, mobile health interventions in clinical trials, it is crucial for researchers to address the security and privacy concerns of patient information according to high ethical standards.
Roy Eagleson   +9 more
doaj   +1 more source

What is the current state of the Multilingual Web of Data? [PDF]

open access: yes, 2012
The Semantic Web is growing at a fast pace, recently boosted by the creation of the Linked Data initiative and principles. Methods, standards, techniques and the state of technology are becoming more mature and therefore are easing the task of ...
Gómez-Pérez, A., Vila-Suero, Daniel
core   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

open access: yesFEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng   +13 more
wiley   +1 more source

Web Services Specific Security Standards

open access: yesProcedia Economics and Finance, 2014
AbstractIn this paper are described the aspects regarding the security within OGSA framework, introducing WS-Security standard – OASIS standard for Web Services security. There are approached the security aspects of the OGSA environment for the delivered architectures P2P – ‘Peer-to-Peer’ and there are presented the recent initiatives for creating a ...
Marian Pompiliu Cristescu   +2 more
openaire   +2 more sources

How the web continues to fail people with disabilities [PDF]

open access: yes, 2008
The digital divide is most often understood as that between the IT haves and have-nots. However, if there is one minority group that can be, and often is excluded from the world wide web, even if they have a computer, it is disabled people.
Kreps, David
core  

Home - About - Disclaimer - Privacy